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Red flag symptoms and signs of mass lesions in the posterior nasal space should be investigated and treated promptly to prevent devastating visual and prognostic consequences.<\/jats:p>","DOI":"10.1136\/bcr-2022-248902","type":"journal-article","created":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T12:32:32Z","timestamp":1646137952000},"page":"e248902","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Rare early presentation of bilateral compressive optic neuropathy with complete vision loss from nasopharyngeal carcinoma"],"prefix":"10.1136","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7828-7943","authenticated-orcid":false,"given":"Yongyao","family":"Kong","sequence":"first","affiliation":[{"name":"Department of Neurology, National Neuroscience Institute, Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gee Jin","family":"Ng","sequence":"additional","affiliation":[{"name":"Department of Neurology, National Neuroscience Institute, Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2022,3,1]]},"reference":[{"key":"2025082711252034000_15.3.e248902.1","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1111\/j.1553-2712.1996.tb03354.x","article-title":"Acute bilateral blindness","volume":"3","author":"Hoover","year":"1996","journal-title":"Acad Emerg Med"},{"key":"2025082711252034000_15.3.e248902.2","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1212\/01.CON.0000348830.42243.03","article-title":"Bilateral visual loss approach, localization, and causes","volume":"15","author":"Glisson","year":"2009","journal-title":"Continuum"},{"key":"2025082711252034000_15.3.e248902.3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2006.06.006"},{"key":"2025082711252034000_15.3.e248902.4","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(19991115)86:10<1912::AID-CNCR6>3.0.CO;2-S"},{"key":"2025082711252034000_15.3.e248902.5","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1038\/sj.eye.6701358","article-title":"Nasopharyngeal carcinoma with orbital invasion","volume":"18","author":"Hsu","year":"2004","journal-title":"Eye"},{"key":"2025082711252034000_15.3.e248902.6","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1080\/01676830.2017.1279658","article-title":"Ophthalmic involvement in nasopharyngeal carcinoma","volume":"36","author":"Wong","year":"2017","journal-title":"Orbit"},{"key":"2025082711252034000_15.3.e248902.7","doi-asserted-by":"crossref","first-page":"1977","DOI":"10.1002\/hed.25177","article-title":"Association between nasopharyngeal carcinoma and risk of optic neuropathy: a population-based cohort study","volume":"40","author":"Fan","year":"2018","journal-title":"Head Neck"},{"key":"2025082711252034000_15.3.e248902.8","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.radonc.2021.08.022","article-title":"Cranial neuropathies in advanced nasopharyngeal carcinoma: neurological recovery after modern radiotherapy and systemic chemotherapy","volume":"163","author":"Chow","year":"2021","journal-title":"Radiother Oncol"},{"key":"2025082711252034000_15.3.e248902.9","doi-asserted-by":"publisher","DOI":"10.1016\/S1044579X02000858"},{"key":"2025082711252034000_15.3.e248902.10","unstructured":". 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