{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T12:40:36Z","timestamp":1782477636694,"version":"3.54.5"},"reference-count":10,"publisher":"BMJ","issue":"5","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2022,4,24]]},"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:p>A man in his 60s, with a medical history of gout, underwent total knee arthroplasty of his right knee followed by expeditious rehabilitation. Seven months after surgery, he was referred to the emergency ward with sudden onset of pain and swelling of his right knee accompanied with fever. Further inquiry revealed no trauma, infection or skin lesions besides a tongue bite several weeks earlier. An impaired range motion of the knee was seen on physical examination along with a tachycardia. Laboratory studies showed a C reactive protein of 345\u2009mg\/L, after which a debridement, antibiotics and implant retention procedure was performed. Intraoperatively obtained synovial fluid showed monosodium urate crystals consistent with crystalline arthropathy (ie, gout). However, unexpectedly, <jats:italic>Streptococcus sanguinis<\/jats:italic> was identified in all microbiological cultures too, confirming a coexistent periprosthetic joint infection. After comprehensive antibiotic treatment and gout flare therapy, this patient made a full recovery with retention of the implant.<\/jats:p>","DOI":"10.1136\/bcr-2022-249154","type":"journal-article","created":{"date-parts":[[2022,5,6]],"date-time":"2022-05-06T12:17:50Z","timestamp":1651839470000},"page":"e249154","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Acute haematogenous periprosthetic joint infection due to <i>Streptococcus sanguinis<\/i> along with coexistent crystalline arthropathy after total knee arthroplasty: a rare combination"],"prefix":"10.1136","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5648-0275","authenticated-orcid":false,"given":"Joost B","family":"Malkus","sequence":"first","affiliation":[{"name":"Departmeny of Surgery, Isala Hospitals, Zwolle, The Netherlands"},{"name":"Department of Orthopaedic Surgery, Medisch Spectrum Twente, Enschede, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louren M","family":"Goedhart","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Medisch Spectrum Twente, Enschede, The Netherlands"},{"name":"Department of Orthopaedic Surgery, University Medical Centre Groningen, Groningen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wiebe C","family":"Verra","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Medisch Spectrum Twente, Enschede, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2022,5,6]]},"reference":[{"key":"2025082801232682000_15.5.e249154.1","doi-asserted-by":"publisher","DOI":"10.1302\/2058-5241.4.180092"},{"key":"2025082801232682000_15.5.e249154.2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cis803"},{"key":"2025082801232682000_15.5.e249154.3","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1016\/j.cmi.2018.10.010","article-title":"Origin and characteristics of haematogenous periprosthetic joint infection","volume":"25","author":"Rakow","year":"2019","journal-title":"Clin Microbiol Infect"},{"key":"2025082801232682000_15.5.e249154.4","doi-asserted-by":"crossref","first-page":"138","DOI":"10.5371\/hp.2018.30.3.138","article-title":"Management of periprosthetic joint infection","volume":"30","author":"Li","year":"2018","journal-title":"Hip Pelvis"},{"key":"2025082801232682000_15.5.e249154.5","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.309.6953.506"},{"key":"2025082801232682000_15.5.e249154.6","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1159\/000089391","article-title":"Acute septic arthritis due to Streptococcus sanguis","volume":"15","author":"Papaioannides","year":"2006","journal-title":"Med Princ Pract"},{"key":"2025082801232682000_15.5.e249154.7","doi-asserted-by":"publisher","DOI":"10.4065\/77.7.709"},{"key":"2025082801232682000_15.5.e249154.8","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1016\/j.jbspin.2016.01.006","article-title":"Crystal-Induced arthritis after arthroplasty: 7 cases","volume":"83","author":"Yahia","year":"2016","journal-title":"Joint Bone Spine"},{"key":"2025082801232682000_15.5.e249154.9","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1097\/NOR.0000000000000021","article-title":"Diagnosis and management of gout in total knee arthroplasty","volume":"33","author":"Buck","year":"2014","journal-title":"Orthop Nurs"},{"key":"2025082801232682000_15.5.e249154.10","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/j.artd.2020.03.003","article-title":"Gout after total knee arthroplasty","volume":"6","author":"Chernoff","year":"2020","journal-title":"Arthroplast Today"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2022-249154","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T08:23:34Z","timestamp":1756369414000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2022-249154"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5]]},"references-count":10,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2022,5,6]]},"published-print":{"date-parts":[[2022,5]]}},"alternative-id":["10.1136\/bcr-2022-249154"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2022-249154","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5]]}}}