{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T18:10:02Z","timestamp":1756318202532,"version":"3.44.0"},"reference-count":7,"publisher":"BMJ","issue":"7","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2022,6,28]]},"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:p>A woman in her late twenties presented with blurring of vision in the right eye for 6 years. Retinoscopy showed a scissoring reflex in the right eye with best spectacle-corrected visual acuity of 20\/40 in the right eye and 20\/20 in the left eye. Slit-lamp examination of the right eye showed superior crescentic thinning with conjunctivalisation and lipid deposition while the left eye was normal. Corneal topography of the right eye showed inverse crab-claw pattern suggestive of Terrien\u2019s marginal degeneration (TMD) and the left eye showed inferior steepening with posterior elevation and thinning suggestive of keratoconus-like topography. This case shows that evaluation of the other apparently normal eye with 20\/20 vision might show changes on topography in cases of unilateral TMD and needs follow-up to assess any further progression.<\/jats:p>","DOI":"10.1136\/bcr-2022-249493","type":"journal-article","created":{"date-parts":[[2022,7,4]],"date-time":"2022-07-04T12:11:27Z","timestamp":1656936687000},"page":"e249493","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Topographic changes in contralateral eye of a case of Terrien\u2019s marginal degeneration"],"prefix":"10.1136","volume":"15","author":[{"given":"Harshita","family":"Nahata","sequence":"first","affiliation":[{"name":"Ophthalmology, Narayana Nethralaya, Bangalore, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harsha","family":"Nagaraja","sequence":"additional","affiliation":[{"name":"Cornea and External Diseases of the Eye, Narayana Nethralaya, Bangalore, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rohit","family":"Shetty","sequence":"additional","affiliation":[{"name":"Refractive Surgery, Narayana Nethralaya, Bangalore, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2022,7,4]]},"reference":[{"key":"2025082710451801000_15.7.e249493.1","first-page":"909","volume-title":"Part 2: diseases of the outer eye","volume":"8","author":"Duke-Elder","year":"1965"},{"key":"2025082710451801000_15.7.e249493.2","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0002-9394(81)90768-6","article-title":"Inflammatory Terrien's marginal corneal disease","volume":"92","author":"Austin","year":"1981","journal-title":"Am J Ophthalmol"},{"key":"2025082710451801000_15.7.e249493.3","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1111\/j.1755-3768.1989.tb07111.x","article-title":"Keratoconus associated with Terrien's marginal degeneration. A clinical and ultrastructural study","volume":"192","author":"Pouliquen","year":"1989","journal-title":"Acta Ophthalmol Suppl"},{"key":"2025082710451801000_15.7.e249493.4","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1097\/00003226-199909000-00017","article-title":"Terrien's marginal degeneration associated with posterior polymorphous dystrophy","volume":"18","author":"Wagoner","year":"1999","journal-title":"Cornea"},{"key":"2025082710451801000_15.7.e249493.5","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.survophthal.2018.09.004","article-title":"Terrien marginal degeneration","volume":"64","author":"Ding","year":"2019","journal-title":"Surv Ophthalmol"},{"key":"2025082710451801000_15.7.e249493.6","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/j.clae.2011.05.002","article-title":"Scanning slit topography: diagnostic boon in presumed unilateral Terrien's marginal degeneration","volume":"34","author":"Fernandes","year":"2011","journal-title":"Cont Lens Anterior Eye"},{"key":"2025082710451801000_15.7.e249493.7","doi-asserted-by":"crossref","first-page":"394","DOI":"10.4103\/0301-4738.116058","article-title":"Imaging modalities in keratoconus","volume":"61","author":"Matalia","year":"2013","journal-title":"Indian J Ophthalmol"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2022-249493","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T17:45:22Z","timestamp":1756316722000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2022-249493"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7]]},"references-count":7,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2022,7,4]]},"published-print":{"date-parts":[[2022,7]]}},"alternative-id":["10.1136\/bcr-2022-249493"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2022-249493","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2022,7]]}}}