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Both anterior and posterior segment findings seem to be within normal limits except for the microcornea. Topography depicts an asymmetric bow tie with superior steeping in both eyes. This case was diagnosed as pure microphthalmos associated with irregular corneal curvature, suggestive of keratoconus without corneal thinning with the help of topography and biometric measurements. Contact lens trial was advised to improve the visual potential. Fitting this patient in RGP lenses has been a challenging task because of narrow palpebral fissure height and small cornea.<\/jats:p>","DOI":"10.1136\/bcr-2022-249534","type":"journal-article","created":{"date-parts":[[2022,7,7]],"date-time":"2022-07-07T12:15:23Z","timestamp":1657196123000},"page":"e249534","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Conventional-based contact lens fitting in pure microphthalmia associated with irregular cornea"],"prefix":"10.1136","volume":"15","author":[{"given":"Manikanda","family":"Prabhu","sequence":"first","affiliation":[{"name":"Cornea and Anterior Segment Department, LV Prasad Eye Institute Kode Venkatadri Chowdary Campus, Vijayawada, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sushank","family":"Bhalerao","sequence":"additional","affiliation":[{"name":"Cornea and Anterior Segment Department, LV Prasad Eye Institute Kode Venkatadri Chowdary Campus, Vijayawada, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5493-7101","authenticated-orcid":false,"given":"Pratik Yeshwant","family":"Gogri","sequence":"additional","affiliation":[{"name":"Cornea and Anterior Segment, LV Prasad Eye Institute, Hyderabad, Telangana, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samruddhi","family":"Dalal","sequence":"additional","affiliation":[{"name":"Cornea and Anterior Segment Department, LV Prasad Eye Institute Kode Venkatadri Chowdary Campus, Vijayawada, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2022,7,7]]},"reference":[{"key":"2025082710363084000_15.7.e249534.1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2018\/2735465","article-title":"Nanophthalmos: a review of the clinical spectrum and genetics","volume":"2018","author":"Carricondo","year":"2018","journal-title":"J Ophthalmol"},{"key":"2025082710363084000_15.7.e249534.2","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1111\/j.1600-0420.1997.tb00788.x","article-title":"Autosomal recessive nanophthalmos","volume":"75","author":"Altinta\u015f","year":"1997","journal-title":"Acta Ophthalmol Scand"},{"key":"2025082710363084000_15.7.e249534.3","doi-asserted-by":"publisher","DOI":"10.1177\/0300060515594195"},{"key":"2025082710363084000_15.7.e249534.4","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.clae.2012.12.002","article-title":"Rgp contact lens fitting in keratoconus using FITSCAN technology","volume":"36","author":"Mandathara","year":"2013","journal-title":"Cont Lens Anterior Eye"},{"key":"2025082710363084000_15.7.e249534.5","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.clae.2013.01.006","article-title":"Comparison of conventional method of contact lens fitting and software based contact lens fitting with Medmont corneal Topographer in eyes with corneal scar","volume":"36","author":"Siddireddy","year":"2013","journal-title":"Cont Lens Anterior Eye"},{"key":"2025082710363084000_15.7.e249534.6","doi-asserted-by":"crossref","unstructured":"Chaudhry M . 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