{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T21:28:33Z","timestamp":1775338113994,"version":"3.50.1"},"reference-count":14,"publisher":"BMJ","issue":"5","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2022,5,5]]},"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:p>An immunocompetent man in his 40s presented with 3\u2009months of mid-thoracic back pain which progressed to include progressive paraesthesias and lower extremity weakness. Investigations revealed thoracic spine osteomyelitis with signs of cord compression. He underwent neurosurgical intervention, including laminectomy, spinal cord decompression and partial resection of an epidural mass. Initial intraoperative biopsy and surgical pathology results were concerning for an acid-fast bacillus as the causative pathogen, and the patient was given empiric therapy for presumed <jats:italic>Mycobacterium tuberculosis<\/jats:italic>. However, microbiology speciation revealed the presence of the non-tuberculous mycobacterium (NTM) <jats:italic>Mycobacterium kansasii<\/jats:italic>, which resulted in an alteration of his antimicrobial therapy. This case highlights the importance of considering NTM as a possible aetiology of spinal osteomyelitis, even among immunocompetent individuals or in low-prevalence regions.<\/jats:p>","DOI":"10.1136\/bcr-2022-249629","type":"journal-article","created":{"date-parts":[[2022,5,31]],"date-time":"2022-05-31T12:42:32Z","timestamp":1654000952000},"page":"e249629","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Non-tuberculous mycobacterial thoracic osteomyelitis in an immunocompetent host: a rare presentation of <i>Mycobacterium kansasii<\/i>"],"prefix":"10.1136","volume":"15","author":[{"given":"Taylor","family":"Becker","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, The University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew","family":"Smith","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, The University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meredith","family":"Parsons","sequence":"additional","affiliation":[{"name":"Department of Pathology, The University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michihiko","family":"Goto","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, The University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2022,5,26]]},"reference":[{"key":"2025082622441411000_15.5.e249629.1","doi-asserted-by":"crossref","DOI":"10.1093\/omcr\/omw087","article-title":"Isolated Mycobacterium kansasii wound infection and Osteomyelitis in an immunocompetent patient","volume":"2016","author":"Turk","year":"2016","journal-title":"Oxf Med Case Reports"},{"key":"2025082622441411000_15.5.e249629.2","doi-asserted-by":"publisher","DOI":"10.1007\/s10156-013-0550-8"},{"key":"2025082622441411000_15.5.e249629.3","doi-asserted-by":"publisher","DOI":"10.3201\/eid1509.081259"},{"key":"2025082622441411000_15.5.e249629.4","first-page":"83","article-title":"A 14-year-old girl with thoracolumbar pain","volume":"11","author":"Haddadzadeh","year":"2014","journal-title":"Kardiochir Torakochirurgia Pol"},{"key":"2025082622441411000_15.5.e249629.5","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200604-571ST"},{"key":"2025082622441411000_15.5.e249629.6","doi-asserted-by":"crossref","DOI":"10.1128\/microbiolspec.TNMI7-0011-2016","article-title":"Mycobacterium kansasii","volume":"5","author":"Johnston","year":"2017","journal-title":"Microbiol Spectr"},{"key":"2025082622441411000_15.5.e249629.7","doi-asserted-by":"crossref","first-page":"185","DOI":"10.4103\/ijmr.IJMR_902_20","article-title":"Epidemiology, diagnosis & treatment of non-tuberculous mycobacterial diseases","volume":"152","author":"Sharma","year":"2020","journal-title":"Indian J Med Res"},{"key":"2025082622441411000_15.5.e249629.8","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2458-10-612"},{"key":"2025082622441411000_15.5.e249629.9","first-page":"R147","article-title":"Opportunist mycobacteria in England and Wales: 1982 to 1994","volume":"6","author":"Lamden","year":"1996","journal-title":"Commun Dis Rep CDR Rev"},{"key":"2025082622441411000_15.5.e249629.10","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-004-4001-4"},{"key":"2025082622441411000_15.5.e249629.11","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2005.09.010"},{"key":"2025082622441411000_15.5.e249629.12","doi-asserted-by":"crossref","first-page":"205","DOI":"10.4103\/0019-5413.201718","article-title":"Nontuberculous mycobacterial infection of the musculoskeletal system in immunocompetent hosts","volume":"51","author":"Gundavda","year":"2017","journal-title":"Indian J Orthop"},{"key":"2025082622441411000_15.5.e249629.13","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.38.4.1426-1429.2000"},{"key":"2025082622441411000_15.5.e249629.14","doi-asserted-by":"crossref","first-page":"673","DOI":"10.3109\/23744235.2015.1040445","article-title":"Nontuberculous mycobacterial osteomyelitis","volume":"47","author":"Bi","year":"2015","journal-title":"Infect Dis"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2022-249629","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T05:44:23Z","timestamp":1756273463000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2022-249629"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5]]},"references-count":14,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2022,5,26]]},"published-print":{"date-parts":[[2022,5]]}},"alternative-id":["10.1136\/bcr-2022-249629"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2022-249629","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5]]}}}