{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T17:40:02Z","timestamp":1756316402883,"version":"3.44.0"},"reference-count":6,"publisher":"BMJ","issue":"12","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2022,11,16]]},"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:p>Lynch syndrome (LS), also known as hereditary non-polyposis colorectal cancer, is an inherited cancer syndrome which increases the risk of developing colorectal cancer and endometrial cancer. Individuals with LS have an increased risk of cancers of the ovary, urinary tract, stomach, small intestine, pancreas, biliary tract, brain and skin. Cancer risk reduction is recommended through chemoprevention (aspirin), surveillance (colonoscopy, assessment of the endometrium and ovaries via USS, aspiration biopsy and tumour marker monitoring; CA125) or risk reduction surgery, that is, total hysterectomy and bilateral salpingo-oophorectomy.<\/jats:p>\n               <jats:p>This is a case of a nulliparous woman in her early 30s with LS and a congenital genital tract malformation. She had a unicornuate (left) uterus and a vestigial (right) uterine horn. There was an inability to obtain a conclusive set of endometrial biopsies in this patient due to the nature of the patient\u2019s congenital uterine abnormality. In this case, surgery was recommended to excise the vestigial horn and fallopian tube in order to optimise surveillance and fertility.<\/jats:p>","DOI":"10.1136\/bcr-2022-249833","type":"journal-article","created":{"date-parts":[[2022,12,2]],"date-time":"2022-12-02T09:00:19Z","timestamp":1669971619000},"page":"e249833","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Surgical management of a congenital genital tract abnormality in a patient with Lynch syndrome"],"prefix":"10.1136","volume":"15","author":[{"given":"Eniola","family":"Olayato-Aribo","sequence":"first","affiliation":[{"name":"Gynaecology, Lancashire Teaching Hospitals NHS Foundation Trust, Preston, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicholas","family":"Wood","sequence":"additional","affiliation":[{"name":"Gynaecology, Lancashire Teaching Hospitals NHS Foundation Trust, Preston, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Divya","family":"Nagaiah","sequence":"additional","affiliation":[{"name":"Gynaecology, Lancashire Teaching Hospitals NHS Foundation Trust, Preston, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Underwood","sequence":"additional","affiliation":[{"name":"Gynaecology, Lancashire Teaching Hospitals NHS Foundation Trust, Preston, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2022,12,2]]},"reference":[{"key":"2025082710195938000_15.12.e249833.1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0215(19990412)81:2<214::AID-IJC8>3.0.CO;2-L"},{"key":"2025082710195938000_15.12.e249833.2","doi-asserted-by":"crossref","first-page":"097","DOI":"10.1055\/s-0032-1313780","article-title":"Endometrial and ovarian cancer in Lynch syndrome","volume":"25","author":"Crispens","year":"2012","journal-title":"Clin Colon Rectal Surg"},{"key":"2025082710195938000_15.12.e249833.3","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1111\/cga.12329","article-title":"Association between hereditary predisposition to common cancers and congenital multimalformations","volume":"60","author":"Kwiatkowski","year":"2020","journal-title":"Congenit Anom"},{"key":"2025082710195938000_15.12.e249833.4","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0127363"},{"key":"2025082710195938000_15.12.e249833.5","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1007\/s13669-013-0051-x","article-title":"The role of the endometriosis fertility index (EFI) and endometriosis scoring systems in predicting infertility outcomes","volume":"2","author":"Cook","year":"2013","journal-title":"Curr Obstet Gynecol Rep"},{"key":"2025082710195938000_15.12.e249833.6","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2009.09.035"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2022-249833","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T17:20:07Z","timestamp":1756315207000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2022-249833"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12]]},"references-count":6,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2022,12,2]]},"published-print":{"date-parts":[[2022,12]]}},"alternative-id":["10.1136\/bcr-2022-249833"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2022-249833","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2022,12]]}}}