{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T00:02:55Z","timestamp":1756425775135,"version":"3.44.0"},"reference-count":9,"publisher":"BMJ","issue":"8","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2022,8,17]]},"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:p>A man in his early 50s presented with a spontaneous large left-sided retroperitoneal haematoma (RPH), on a background of therapeutic anticoagulation with warfarin for homozygous factor V Leiden. His international normalised ratio was found to be supra-therapeutic at 9.0 on presentation. He was treated non-operatively with prompt reversal of the coagulopathy and close monitoring. On day 4 of the admission, the patient reported scrotal pain and swelling. An urgent scrotal ultrasound revealed infarction of the left testis and the patient was taken to an emergency scrotal exploration. Intraoperatively, the left testis was found to be no longer viable with the left spermatic vein and venules completely thrombosed with extensive clots, while the left testicular artery remained intact. Consequently, a left orchidectomy was performed. Therapeutic anticoagulation was recommenced on day 3 postoperatively. It is thought that the large RPH caused extrinsic compression of the left testicular vein, in addition to the patient\u2019s pre-existing factor V Leiden, which resulted in thrombosis of the blood vessel.<\/jats:p>","DOI":"10.1136\/bcr-2022-249913","type":"journal-article","created":{"date-parts":[[2022,8,25]],"date-time":"2022-08-25T12:45:27Z","timestamp":1661431527000},"page":"e249913","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Left testicular venous infarction secondary to large spontaneous retroperitoneal haematoma compressing left testicular vein: a case report"],"prefix":"10.1136","volume":"15","author":[{"given":"Thomas","family":"Vu","sequence":"first","affiliation":[{"name":"Department of General Surgery, Alfred Health, Melbourne, Victoria, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sivaneswaran","family":"Lechmiannandan","sequence":"additional","affiliation":[{"name":"Department of Medicine at Alfred Medical Research and Education Precinct, Monash University, Melbourne, Victoria, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah","family":"Birks","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Alfred Health, Melbourne, Victoria, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeremy","family":"Grummet","sequence":"additional","affiliation":[{"name":"Department of Medicine at Alfred Medical Research and Education Precinct, Monash University, Melbourne, Victoria, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2022,8,25]]},"reference":[{"key":"2025082800175875000_15.8.e249913.1","doi-asserted-by":"crossref","first-page":"1604","DOI":"10.1111\/j.1742-1241.2007.01494.x","article-title":"Management of spontaneous and iatrogenic retroperitoneal haemorrhage: conservative management, endovascular intervention or open surgery?","volume":"62","author":"Chan","year":"2008","journal-title":"Int J Clin Pract"},{"key":"2025082800175875000_15.8.e249913.2","doi-asserted-by":"crossref","first-page":"1618","DOI":"10.1007\/s00268-009-0048-9","article-title":"Local and systemic consequences of large retroperitoneal clot burdens","volume":"33","author":"Loor","year":"2009","journal-title":"World J Surg"},{"key":"2025082800175875000_15.8.e249913.3","unstructured":"Dorosh J , Lin JC . Retroperitoneal Bleeding. StatPearls [Internet], 2020."},{"key":"2025082800175875000_15.8.e249913.4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jemermed.2011.06.006"},{"key":"2025082800175875000_15.8.e249913.5","doi-asserted-by":"crossref","first-page":"87","DOI":"10.3400\/avd.cr.18-00110","article-title":"Inferior vena cava compression caused by a retroperitoneal hematoma following an abdominal aortic aneurysm rupture","volume":"12","author":"Ikeda","year":"2019","journal-title":"Ann Vasc Dis"},{"key":"2025082800175875000_15.8.e249913.6","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-200307000-00004"},{"key":"2025082800175875000_15.8.e249913.7","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1111\/ejh.12985","article-title":"Testicular vein thrombosis: incidence of recurrent venous thromboembolism and survival","volume":"100","author":"Lenz","year":"2018","journal-title":"Eur J Haematol"},{"key":"2025082800175875000_15.8.e249913.8","doi-asserted-by":"crossref","first-page":"57","DOI":"10.7863\/jum.1995.14.1.57","article-title":"Sonographic appearance of acute testicular venous infarction in a patient with a hypercoagulable state","volume":"14","author":"Wu","year":"1995","journal-title":"J Ultrasound Med"},{"key":"2025082800175875000_15.8.e249913.9","first-page":"26","article-title":"Patient with antiphospholipid syndrome presenting with testicular torsion-like symptoms","volume":"15","author":"Srivastava","year":"2017","journal-title":"Urol Case Rep"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2022-249913","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T07:18:09Z","timestamp":1756365489000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2022-249913"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8]]},"references-count":9,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2022,8,25]]},"published-print":{"date-parts":[[2022,8]]}},"alternative-id":["10.1136\/bcr-2022-249913"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2022-249913","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2022,8]]}}}