{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T22:44:40Z","timestamp":1792363480403,"version":"4.4.0"},"reference-count":14,"publisher":"BMJ","issue":"4","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2022,12,22]]},"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:p>Tracheobronchopathia osteochondroplastica (TO) is a rare condition affecting the lumen of the tracheobronchial tree. It is characterised by the presence of multiple osseous and cartilaginous nodules with posterior wall sparing. While it is a benign condition, it can cause narrowing of the tracheal lumen and subglottis to varying degrees. Approximately 400 cases have been reported worldwide, with an incidence of 0.3% in autopsies and between 1 in 125 and 1 in 5000 on bronchoscopy. As most patients are asymptomatic, this may contribute to underdiagnoses and relative low incidence. Severity of the condition is often unrelated to patient symptomatology. We present a patient with one of the most severe cases of TO seen at our institution. Despite being asymptomatic, significant tracheal and bronchial narrowing was found incidentally on laryngobronchoscopy.<\/jats:p>","DOI":"10.1136\/bcr-2022-249976","type":"journal-article","created":{"date-parts":[[2023,4,13]],"date-time":"2023-04-13T13:30:11Z","timestamp":1681392611000},"page":"e249976","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Severe tracheobronchopathia osteochondroplastica in an asymptomatic patient"],"prefix":"10.1136","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1999-5880","authenticated-orcid":false,"given":"Giovanni Francesco","family":"Dall'Amico","sequence":"first","affiliation":[{"name":"ENT Department, Imperial College Healthcare NHS Trust, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dave","family":"Sharma","sequence":"additional","affiliation":[{"name":"ENT Department, Imperial College Healthcare NHS Trust, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lulu","family":"Ritchie","sequence":"additional","affiliation":[{"name":"ENT Department, Imperial College Healthcare NHS Trust, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guri","family":"Sandhu","sequence":"additional","affiliation":[{"name":"National Centre for Airway Reconstruction, Imperial College London, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2023,4,13]]},"reference":[{"key":"2025082708273644000_16.4.e249976.1","doi-asserted-by":"crossref","unstructured":"Lundgren R , Stjernberg NL , Tracheobronchopathia osteochondroplastica . 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Groupe d\u2019etudes et de recherche sur les maladies \u201corphelines\u201d pulmonaires (GERM\"O\"P). tracheobronchopathia osteochondroplastica: a study of 41 patients. 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