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Histopathological analysis of the specimen obtained by surgical lung biopsy showed a desquamative interstitial pneumonia (DIP) pattern, with lymphocyte and plasma cell infiltrates in the alveolar septa; the ratio of IgG and IgG4-positive cells was more than 90%. He quit smoking, but the radiological findings worsened. Based on the pathological findings, we diagnosed the patient with DIP due to IgG4-related lung disease. Prednisolone was initiated, and the symptoms and radiological findings improved.<\/jats:p>","DOI":"10.1136\/bcr-2022-249998","type":"journal-article","created":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T12:10:14Z","timestamp":1659355814000},"page":"e249998","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["IgG4-related lung disease with a desquamative interstitial pneumonia pattern radiologically and pathologically"],"prefix":"10.1136","volume":"15","author":[{"given":"Shingo","family":"Tsuneyoshi","sequence":"first","affiliation":[{"name":"Division of Respirology, Neurology, and Rheumatology, Department of Medicine, Kurume University School of Medicine, Kurume, Fukuoka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2274-4599","authenticated-orcid":false,"given":"Yoshiaki","family":"Zaizen","sequence":"additional","affiliation":[{"name":"Division of 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