{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T03:06:50Z","timestamp":1789528010625,"version":"build-2803163510"},"reference-count":21,"publisher":"BMJ","issue":"8","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2022,7,28]]},"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:p>Primary adenoid cystic carcinoma (ACC) of the trachea is a rare entity, with a 5-year survival between 50% and 80% for resectable cases and 30% in case of unresectable disease. We report a case of a primary ACC on a woman in her 70s that presented with a drawn-out history of dyspnoea. She was diagnosed with an unresectable obstructive tumour of the trachea, which required the placement of a Y-shaped stent. The patient underwent concomitant chemoradiotherapy, with partial response, and is still in follow-up, without evidence of disease progression.<\/jats:p>","DOI":"10.1136\/bcr-2022-250227","type":"journal-article","created":{"date-parts":[[2022,8,9]],"date-time":"2022-08-09T11:20:58Z","timestamp":1660044058000},"page":"e250227","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Primary adenoid cystic carcinoma of the trachea: an elusive diagnosis of chronic dyspnoea"],"prefix":"10.1136","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6707-7673","authenticated-orcid":false,"given":"Cec\u00edlia","family":"Caramujo","sequence":"first","affiliation":[{"name":"Department of Medical Oncology, Instituto Portugu\u00eas de Oncologia de Coimbra Francisco Gentil EPE, Coimbra, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafael Moiteiro","family":"da Cruz","sequence":"additional","affiliation":[{"name":"Department of Pathology, Hospital de Santa Maria, Lisboa, Portugal"},{"name":"Universidade de Lisboa Faculdade de Medicina, Lisboa, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui Vale","family":"Marques","sequence":"additional","affiliation":[{"name":"Department of Radiotherapy, Instituto Portugu\u00eas de Oncologia de Coimbra Francisco Gentil EPE, Coimbra, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emanuel","family":"Jesus","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Instituto Portugu\u00eas de Oncologia de Coimbra Francisco Gentil EPE, Coimbra, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2022,8,9]]},"reference":[{"key":"2025082703454868000_15.8.e250227.1","doi-asserted-by":"publisher","DOI":"10.1016\/S1010-7940(01)00597-8"},{"key":"2025082703454868000_15.8.e250227.2","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-006-9229-z"},{"key":"2025082703454868000_15.8.e250227.3","doi-asserted-by":"publisher","DOI":"10.1097\/COC.0b013e3181cae8ab"},{"key":"2025082703454868000_15.8.e250227.4","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2004.05.064"},{"key":"2025082703454868000_15.8.e250227.5","unstructured":"Mehrad M , Nicholson AG , Farver CF . Adenoid cystic carcinoma of the lung. In: Who classification of tumours editorial board. thoracic tumours. Lyon (France): International Agency for Research on Cancer, 2021."},{"key":"2025082703454868000_15.8.e250227.6","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1097\/MCP.0000000000000181","article-title":"Malignant tracheal tumors: a review of current diagnostic and management strategies","volume":"21","author":"Sherani","year":"2015","journal-title":"Curr Opin Pulm Med"},{"key":"2025082703454868000_15.8.e250227.7","doi-asserted-by":"publisher","DOI":"10.1016\/j.thorsurg.2013.09.004"},{"key":"2025082703454868000_15.8.e250227.8","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1097\/MCP.0000000000000181","article-title":"Malignant tracheal tumors: a review of current diagnostic and management strategies","volume":"21","author":"Sherani","year":"2015","journal-title":"Curr Opin Pulm Med"},{"key":"2025082703454868000_15.8.e250227.9","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21388"},{"key":"2025082703454868000_15.8.e250227.10","unstructured":"U.S. Department Of Health And Human Services . Common Terminology Criteria for Adverse Events (CTCAE - Version 5.0), 2017."},{"key":"2025082703454868000_15.8.e250227.11","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2008.10.026"},{"key":"2025082703454868000_15.8.e250227.12","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19890615)63:12<2429::AID-CNCR2820631210>3.0.CO;2-0"},{"key":"2025082703454868000_15.8.e250227.13","doi-asserted-by":"publisher","DOI":"10.1016\/0167-8140(89)90139-4"},{"key":"2025082703454868000_15.8.e250227.14","doi-asserted-by":"publisher","DOI":"10.1053\/clon.2000.9171"},{"key":"2025082703454868000_15.8.e250227.15","first-page":"143","article-title":"Primary chemoradiation as definitive treatment for unresectable cancer of the trachea","volume":"10","author":"Videtic","year":"2003","journal-title":"Can Respir J"},{"key":"2025082703454868000_15.8.e250227.16","doi-asserted-by":"publisher","DOI":"10.1097\/01.coc.0000203756.36866.17"},{"key":"2025082703454868000_15.8.e250227.17","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2007.13.7273"},{"key":"2025082703454868000_15.8.e250227.18","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1245\/s10434-008-0241-3","article-title":"Undertreatment of tracheal carcinoma: multidisciplinary audit of epidemiologic data","volume":"16","author":"Honings","year":"2009","journal-title":"Ann Surg Oncol"},{"key":"2025082703454868000_15.8.e250227.19","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1186\/s13014-021-01770-0","article-title":"Clinical features, treatment and outcomes in patients with tracheal adenoid cystic carcinoma: a systematic literature review","volume":"16","author":"Ran","year":"2021","journal-title":"Radiat Oncol"},{"key":"2025082703454868000_15.8.e250227.20","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.clon.2017.10.012","article-title":"Radiotherapy for Tracheal-Bronchial cystic adenoid carcinomas","volume":"30","author":"Levy","year":"2018","journal-title":"Clin Oncol"},{"key":"2025082703454868000_15.8.e250227.21","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1186\/s13014-019-1323-z","article-title":"Primary adenoid cystic carcinoma of the trachea: clinical outcome of 38 patients after interdisciplinary treatment in a single institution","volume":"14","author":"H\u00f6gerle","year":"2019","journal-title":"Radiat Oncol"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2022-250227","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T10:45:58Z","timestamp":1756291558000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2022-250227"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8]]},"references-count":21,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2022,8,9]]},"published-print":{"date-parts":[[2022,8]]}},"alternative-id":["10.1136\/bcr-2022-250227"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2022-250227","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,8]]}}}