{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T00:58:00Z","timestamp":1768525080883,"version":"3.49.0"},"reference-count":14,"publisher":"BMJ","issue":"10","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2022,8,23]]},"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:p>Preliminary data on HIV-positive donor to HIV-positive recipient kidney transplantation suggest promising patient outcomes without adverse events. This is an important step in expanding the donor pool and opportunity for transplantation in HIV-positive patients.<\/jats:p>\n               <jats:p>We herein report the first case of HIV-positive donor to HIV-positive recipient kidney transplantation in Denmark. Our patient has demonstrated a successful post-transplant course with excellent 1-year graft function, no rejection episodes, good virological control with undetectable HIV RNA, no signs of HIV-associated nephropathy, and no superinfections or opportunistic infections.<\/jats:p>\n               <jats:p>This case corroborates findings from previous studies showing that kidney transplantation from carefully selected HIV-infected donors to carefully selected HIV-infected recipients seems to be a safe and effective treatment option, and supports the opportunity to expand the organ donor pool for this group of patients with end-stage renal disease.<\/jats:p>","DOI":"10.1136\/bcr-2022-250290","type":"journal-article","created":{"date-parts":[[2022,10,21]],"date-time":"2022-10-21T09:55:11Z","timestamp":1666346111000},"page":"e250290","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Kidney transplantation from an HIV-positive deceased donor to an HIV-positive recipient"],"prefix":"10.1136","volume":"15","author":[{"given":"Christiane","family":"Lyngberg-Larsen","sequence":"first","affiliation":[{"name":"Department of Nephrology, Aarhus University Hospital, Aarhus, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alex","family":"Lund Laursen","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5977-2812","authenticated-orcid":false,"given":"Lara Aygen","family":"\u00d8zbay","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Aarhus University Hospital, Aarhus, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2022,10,21]]},"reference":[{"key":"2025082703172258000_15.10.e250290.1","first-page":"1655","article-title":"Kidney diseases associated with human immunodeficiency virus infection","volume":"378","author":"Cohen","year":"2018","journal-title":"N Engl J Med"},{"key":"2025082703172258000_15.10.e250290.2","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfv207"},{"key":"2025082703172258000_15.10.e250290.3","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2018.8431"},{"key":"2025082703172258000_15.10.e250290.4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc0900837"},{"key":"2025082703172258000_15.10.e250290.5","doi-asserted-by":"crossref","first-page":"205435811769579","DOI":"10.1177\/2054358117695792","article-title":"First Canadian case report of kidney transplantation from an HIV-positive donor to an HIV-positive recipient","volume":"4","author":"Ambaraghassi","year":"2017","journal-title":"Can J Kidney Health Dis"},{"key":"2025082703172258000_15.10.e250290.6","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1093\/ckj\/sfx109","article-title":"First UK case report of kidney transplantation from an HIV-infected deceased donor to two HIV-infected recipients","volume":"11","author":"Nolan","year":"2018","journal-title":"Clin Kidney J"},{"key":"2025082703172258000_15.10.e250290.7","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1056\/NEJMc1903013","article-title":"Longer-term outcomes of HIV-positive-to-HIV-positive renal transplantation","volume":"381","author":"Selhorst","year":"2019","journal-title":"N Engl J Med"},{"key":"2025082703172258000_15.10.e250290.8","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1056\/NEJMoa1408896","article-title":"HIV-positive-to-HIV-positive kidney transplantation--results at 3 to 5 years","volume":"372","author":"Muller","year":"2015","journal-title":"N Engl J Med"},{"key":"2025082703172258000_15.10.e250290.9","doi-asserted-by":"crossref","DOI":"10.1111\/tid.13183","article-title":"Kidney transplantation from an HIV-positive cadaveric donor","volume":"21","author":"Varotti","year":"2019","journal-title":"Transpl Infect Dis"},{"key":"2025082703172258000_15.10.e250290.10","doi-asserted-by":"crossref","first-page":"e611","DOI":"10.1016\/S2352-3018(20)30200-9","article-title":"Outcomes of donor-derived superinfection screening in HIV-positive to HIV-positive kidney and liver transplantation: a multicentre, prospective, observational study","volume":"7","author":"Bonny","year":"2020","journal-title":"Lancet HIV"},{"key":"2025082703172258000_15.10.e250290.11","doi-asserted-by":"crossref","first-page":"1754","DOI":"10.1111\/ajt.16205","article-title":"A prospective multicenter pilot study of HIV\u2010positive deceased donor to HIV\u2010positive recipient kidney transplantation: hope in action","volume":"21","author":"Durand","year":"2021","journal-title":"Am J Transplant"},{"key":"2025082703172258000_15.10.e250290.12","doi-asserted-by":"crossref","first-page":"1492","DOI":"10.1097\/TP.0000000000003485","article-title":"Kidney transplantation in HIV-positive patients: current practice and management strategies","volume":"105","author":"Muller","year":"2021","journal-title":"Transplantation"},{"key":"2025082703172258000_15.10.e250290.13","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1001197"},{"key":"2025082703172258000_15.10.e250290.14","first-page":"435","article-title":"Survival in HIV-positive transplant recipients compared with transplant candidates and with HIV-negative controls","volume":"30","author":"Roland","year":"2016","journal-title":"AIDS"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2022-250290","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T10:17:29Z","timestamp":1756289849000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2022-250290"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10]]},"references-count":14,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2022,10,21]]},"published-print":{"date-parts":[[2022,10]]}},"alternative-id":["10.1136\/bcr-2022-250290"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2022-250290","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,10]]}}}