{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T00:06:49Z","timestamp":1756339609909,"version":"3.44.0"},"reference-count":5,"publisher":"BMJ","issue":"7","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2022,5,23]]},"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:p>\n                  <jats:italic>Strongyloides stercoralis<\/jats:italic> is a helminth found in the soil and transmitted to humans through larval penetration of the skin. It is endemic across most of the tropical regions of the world. Infection with <jats:italic>S. stercoralis<\/jats:italic> commonly causes minimal or mild symptoms. This case report describes an interesting final diagnosis for a woman presenting with persistent nausea, vomiting and epigastric pain. Her evaluation included imaging and oesophagogastroduodenoscopy with biopsy. Her biopsy results revealed oesophageal candidiasis and disseminated strongyloidiasis. Important historical clues in this case included previous prolonged treatment with steroids, recent diagnosis of gram-negative bacteraemia, prior residence in Rwanda, and unknown predeparture treatment for <jats:italic>S. stercoralis<\/jats:italic>. She was ultimately treated with fluconazole and ivermectin with marked improvement in her symptoms.<\/jats:p>","DOI":"10.1136\/bcr-2022-250559","type":"journal-article","created":{"date-parts":[[2022,7,14]],"date-time":"2022-07-14T10:55:14Z","timestamp":1657796114000},"page":"e250559","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Disseminated strongyloidiasis after prolonged treatment with corticosteroids"],"prefix":"10.1136","volume":"15","author":[{"given":"Caitlin","family":"Mahoney","sequence":"first","affiliation":[{"name":"Family Medicine, Cone Health, Greensboro, North Carolina, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carina Murphy","family":"Brown","sequence":"additional","affiliation":[{"name":"Family Medicine, Cone Health, Greensboro, North Carolina, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brittany","family":"McIntyre","sequence":"additional","affiliation":[{"name":"Family Medicine, Cone Health, Greensboro, North Carolina, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"Neal","sequence":"additional","affiliation":[{"name":"Family Medicine, Cone Health, Greensboro, North Carolina, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2022,7,14]]},"reference":[{"key":"2025082713033603000_15.7.e250559.1","doi-asserted-by":"crossref","DOI":"10.3390\/pathogens9060468","article-title":"The Global Prevalence of Strongyloides stercoralis Infection","volume":"9","author":"Buonfrate","year":"2020","journal-title":"Pathogens"},{"unstructured":"Centers for Disease Control and Prevention . Oversease refugee health guidance [Internet]. Atlanta: Centers for Disease Control and Prevention, 2021. Available: https:\/\/www.cdc.gov\/immigrantrefugeehealth\/guidelines\/overseas-guidelines.html.","key":"2025082713033603000_15.7.e250559.2"},{"key":"2025082713033603000_15.7.e250559.3","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.4269\/ajtmh.18-0895","article-title":"Morbidity Associated with Chronic Strongyloides stercoralis Infection: A Systematic Review and Meta-Analysis","volume":"100","author":"Tamarozzi","year":"2019","journal-title":"Am J Trop Med Hyg"},{"unstructured":"World Health Organization . A parasitic infection that can turn fatal with administration of corticosteroids [Internet]. Geneva: World Health Organization, 2020. Available: https:\/\/www.who.int\/news\/item\/17-12-2020-a-parasitic-infection-that-can-turn-fatal-with-administration-of-corticosteroids","key":"2025082713033603000_15.7.e250559.4"},{"unstructured":"Centers for Disease Control and Prevention . CDC \u2013 Strongyloides \u2013 resources for health professionals [Internet]. Atlanta: Centers for Disease Control and Prevention, 2020. Available: https:\/\/www.cdc.gov\/parasites\/strongyloides\/health_professionals\/index.html","key":"2025082713033603000_15.7.e250559.5"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2022-250559","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T20:03:43Z","timestamp":1756325023000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2022-250559"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7]]},"references-count":5,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2022,7,14]]},"published-print":{"date-parts":[[2022,7]]}},"alternative-id":["10.1136\/bcr-2022-250559"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2022-250559","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2022,7]]}}}