{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T14:40:02Z","timestamp":1756305602894,"version":"3.44.0"},"reference-count":18,"publisher":"BMJ","issue":"7","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2022,6,19]]},"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:p>Acute colonic pseudo-obstruction, also known as Ogilvie\u2019s syndrome, is a rare condition involving acute large bowel dilatation without mechanical obstruction. Management begins with conservative treatment and may include pharmacological therapy, colonoscopic decompression and surgery. Timely resolution is important due to the increased risk of bowel perforation and ischaemia associated with colonic dilatation. However, conditions such as neutropenia that place patients at an elevated risk of infection may limit treatment options. We report a case of acute colonic pseudo-obstruction in a neutropenic elderly man resistant to conservative measures and neostigmine and discuss the additional management considerations in an immunocompromised patient.<\/jats:p>","DOI":"10.1136\/bcr-2022-250633","type":"journal-article","created":{"date-parts":[[2022,7,6]],"date-time":"2022-07-06T12:00:53Z","timestamp":1657108853000},"page":"e250633","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Management of acute colonic pseudo-obstruction in a neutropenic patient"],"prefix":"10.1136","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9389-8953","authenticated-orcid":false,"given":"Suzanne","family":"Xu","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shreyak","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Farid","family":"Jadbabaie","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2022,7,6]]},"reference":[{"key":"2025082707261460000_15.7.e250633.1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.6480"},{"key":"2025082707261460000_15.7.e250633.2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02555027"},{"key":"2025082707261460000_15.7.e250633.3","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2005.02668.x"},{"key":"2025082707261460000_15.7.e250633.4","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1016\/j.gie.2018.12.004","article-title":"Safety of endoscopy in cancer patients with thrombocytopenia and neutropenia","volume":"89","author":"Abu-Sbeih","year":"2019","journal-title":"Gastrointest Endosc"},{"key":"2025082707261460000_15.7.e250633.5","doi-asserted-by":"crossref","first-page":"42","DOI":"10.3748\/wjg.v23.i1.42","article-title":"Neutropenic enterocolitis","volume":"23","author":"Rodrigues","year":"2017","journal-title":"World J Gastroenterol"},{"key":"2025082707261460000_15.7.e250633.6","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2036.2001.01088.x"},{"key":"2025082707261460000_15.7.e250633.7","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1007\/BF02553265","article-title":"Ogilvie's syndrome (acute colonic pseudo-obstruction): review of the literature (October 1948 to March 1980) and report of four additional cases","volume":"25","author":"Nanni","year":"1982","journal-title":"Dis Colon Rectum"},{"key":"2025082707261460000_15.7.e250633.8","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.ejogrb.2017.04.028","article-title":"Postpartum acute colonic pseudo-obstruction (Ogilvie's syndrome): a systematic review of case reports and case series","volume":"214","author":"Jayaram","year":"2017","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"2025082707261460000_15.7.e250633.9","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1055\/s-0035-1549100","article-title":"Acute colonic pseudoobstruction","volume":"28","author":"Chudzinski","year":"2015","journal-title":"Clin Colon Rectal Surg"},{"key":"2025082707261460000_15.7.e250633.10","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.amsu.2014.04.002","article-title":"Neostigmine for acute colonic pseudo-obstruction: a meta-analysis","volume":"3","author":"Valle","year":"2014","journal-title":"Ann Med Surg"},{"key":"2025082707261460000_15.7.e250633.11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2004.01900.x"},{"key":"2025082707261460000_15.7.e250633.12","doi-asserted-by":"crossref","first-page":"2002","DOI":"10.3748\/wjg.v13.i13.2002","article-title":"Treatment of pediatric Ogilvie's syndrome with low-dose erythromycin: a case report","volume":"13","author":"Jiang","year":"2007","journal-title":"World J Gastroenterol"},{"key":"2025082707261460000_15.7.e250633.13","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1097\/00004836-199108000-00024","article-title":"Erythromycin as therapy for acute colonic pseudo-obstruction (Ogilvie's syndrome)","volume":"13","author":"Bonacini","year":"1991","journal-title":"J Clin Gastroenterol"},{"key":"2025082707261460000_15.7.e250633.14","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1016\/0140-6736(91)91026-Q","article-title":"Erythromycin for reflex ileus in Ogilvie\u2019s syndrome","volume":"337","author":"Armstrong","year":"1991","journal-title":"The Lancet"},{"key":"2025082707261460000_15.7.e250633.15","doi-asserted-by":"publisher","DOI":"10.1007\/BF02251964"},{"key":"2025082707261460000_15.7.e250633.16","doi-asserted-by":"publisher","DOI":"10.1007\/BF00590926"},{"key":"2025082707261460000_15.7.e250633.17","doi-asserted-by":"crossref","DOI":"10.1016\/j.gie.2009.03.885","article-title":"Utility and safety of endoscopic procedures in neutropenic patients with gastrointestinal bleeding","volume":"69","author":"Jafri","year":"2009","journal-title":"Gastrointest Endosc"},{"key":"2025082707261460000_15.7.e250633.18","doi-asserted-by":"crossref","first-page":"13166","DOI":"10.3748\/wjg.v21.i46.13166","article-title":"Endoscopy in neutropenic and\/or thrombocytopenic patients","volume":"21","author":"Tong","year":"2015","journal-title":"World J Gastroenterol"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2022-250633","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T14:26:24Z","timestamp":1756304784000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2022-250633"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7]]},"references-count":18,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2022,7,6]]},"published-print":{"date-parts":[[2022,7]]}},"alternative-id":["10.1136\/bcr-2022-250633"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2022-250633","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2022,7]]}}}