{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T12:16:20Z","timestamp":1756383380813,"version":"3.44.0"},"reference-count":14,"publisher":"BMJ","issue":"12","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2022,11,17]]},"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:p>A woman in her 40s presented with a 3-month-long history of fever and tender erythematous bullous skin lesions not responsive to antibiotics. There had been no previous gastrointestinal, respiratory or urinary infection, nor did she have any history of autoimmune disease, drug reaction or vasculitis.<\/jats:p>\n               <jats:p>Histological evaluation of skin biopsy showed diffuse dense neutrophilic infiltrates located in dermis diagnostic of Sweet syndrome. Haematological investigations showed leucocytosis with circulating immature cells, which on further investigations with bone marrow biopsy, were evident of chronic myelogenous leukaemia in the accelerated phase. Sweet syndrome was the presenting characteristic of chronic myelogenous leukaemia in this case, which is a rare association. Investigating unusual skin lesions can aid in the suspicion of underlying cancer, allowing for prompt action.<\/jats:p>","DOI":"10.1136\/bcr-2022-250755","type":"journal-article","created":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T13:50:36Z","timestamp":1669902636000},"page":"e250755","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Bullous Sweet syndrome as a presentation of chronic myelogenous leukaemia"],"prefix":"10.1136","volume":"15","author":[{"given":"Syeda Wajiha","family":"Abbas","sequence":"first","affiliation":[{"name":"Internal Medicine, Aga Khan University, Karachi, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zarnain","family":"Shah","sequence":"additional","affiliation":[{"name":"Internal Medicine, Aga Khan University, Karachi, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad Usman","family":"Shaikh","sequence":"additional","affiliation":[{"name":"Pathology and Laboratory Medicine and Oncology, Aga Khan University, Karachi, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2022,12,1]]},"reference":[{"key":"2025082804295762000_15.12.e250755.1","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1053\/j.semdp.2019.01.001","article-title":"Cutaneous paraneoplastic syndromes","volume":"36","author":"Wick","year":"2019","journal-title":"Semin Diagn Pathol"},{"key":"2025082804295762000_15.12.e250755.2","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2019.00414","article-title":"Insights into the pathogenesis of sweet's syndrome","volume":"10","author":"Heath","year":"2019","journal-title":"Front Immunol"},{"key":"2025082804295762000_15.12.e250755.3","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1159\/000494974","article-title":"Pregnancy-induced sweet's syndrome treated with infliximab","volume":"28","author":"Smolovic","year":"2019","journal-title":"Med Princ Pract"},{"key":"2025082804295762000_15.12.e250755.4","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdu490"},{"key":"2025082804295762000_15.12.e250755.5","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1172-2-34"},{"key":"2025082804295762000_15.12.e250755.6","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19931101)72:9<2723::AID-CNCR2820720933>3.0.CO;2-F"},{"key":"2025082804295762000_15.12.e250755.7","doi-asserted-by":"publisher","DOI":"10.1016\/0738-081X(93)90112-P"},{"key":"2025082804295762000_15.12.e250755.8","article-title":"Bullous variant of sweet's syndrome as a consequence of radioiodine contrast exposure","volume":"10","author":"Bhat","year":"2018","journal-title":"Cureus"},{"key":"2025082804295762000_15.12.e250755.9","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1007\/s12308-014-0206-3","article-title":"A rare case of subcutaneous Sweet\u2019s syndrome in a patient with chronic myelogenous leukemia: a case report and review of the literature","volume":"1","author":"Wang","year":"2014","journal-title":"J Hematop"},{"key":"2025082804295762000_15.12.e250755.10","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1995.tb02686.x"},{"key":"2025082804295762000_15.12.e250755.11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2004.12.028"},{"key":"2025082804295762000_15.12.e250755.12","doi-asserted-by":"crossref","first-page":"112","DOI":"10.4103\/2278-0513.125816","article-title":"Sweet\u2019s syndrome in accelerated chronic myelogenous leukemia: a case report and review of literature","volume":"3","author":"Kapoor","year":"2014","journal-title":"Clin Cancer Investig J"},{"key":"2025082804295762000_15.12.e250755.13","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.141.3.368"},{"key":"2025082804295762000_15.12.e250755.14","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1016\/j.humpath.2013.10.029","article-title":"Systemic lupus erythematosus-associated neutrophilic dermatosis--an underrecognized neutrophilic dermatosis in patients with systemic lupus erythematosus","volume":"45","author":"Larson","year":"2014","journal-title":"Hum Pathol"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2022-250755","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T11:30:05Z","timestamp":1756380605000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2022-250755"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12]]},"references-count":14,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2022,12,1]]},"published-print":{"date-parts":[[2022,12]]}},"alternative-id":["10.1136\/bcr-2022-250755"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2022-250755","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2022,12]]}}}