{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T16:02:11Z","timestamp":1787241731793,"version":"build-2736575974"},"reference-count":17,"publisher":"BMJ","issue":"11","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2022,10,29]]},"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:p>\n                    Hyperammonaemia syndrome secondary to\n                    <jats:italic>Ureaplasma<\/jats:italic>\n                    spp. infection is well documented in the post-lung transplant population. We report a case of a man in his fifties with hyperammonaemia syndrome secondary to disseminated\n                    <jats:italic>Ureaplasma parvum<\/jats:italic>\n                    infection. This occurred in the context of immunosuppression for chronic graft versus host disease and six\u2009years following an allogeneic stem cell transplant for diffuse large B-cell lymphoma. Following treatment of\n                    <jats:italic>U. parvum<\/jats:italic>\n                    septic arthritis with ciprofloxacin and doxycycline, the patient experienced a full neurological recovery, and continues on suppressive doxycycline therapy with no recurrence of symptoms to date.\n                  <\/jats:p>","DOI":"10.1136\/bcr-2022-250852","type":"journal-article","created":{"date-parts":[[2022,11,9]],"date-time":"2022-11-09T10:35:23Z","timestamp":1667990123000},"page":"e250852","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["Hyperammonaemia syndrome in disseminated\n                    <i>Ureaplasma parvum<\/i>\n                    infection"],"prefix":"10.1136","volume":"15","author":[{"given":"Nadiya","family":"Brell","sequence":"first","affiliation":[{"name":"University of New South Wales Faculty of Medicine, Sydney, New South Wales, Australia"},{"name":"Infectious Diseases, Prince of Wales Hospital and Community Health Services, Randwick, New South Wales, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristen","family":"Overton","sequence":"additional","affiliation":[{"name":"University of New South Wales Faculty of Medicine, Sydney, New South Wales, Australia"},{"name":"Infectious Diseases, Prince of Wales Hospital and Community Health Services, Randwick, New South Wales, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3502-7636","authenticated-orcid":false,"given":"Milton J","family":"Micallef","sequence":"additional","affiliation":[{"name":"Infectious Diseases, Prince of Wales Hospital and Community Health Services, Randwick, New South Wales, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siobhan","family":"Hurley","sequence":"additional","affiliation":[{"name":"Infectious Diseases, Prince of Wales Hospital and Community Health Services, Randwick, New South Wales, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2022,11,9]]},"reference":[{"key":"2025082711453117000_15.11.e250852.1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.18.4.757-789.2005"},{"key":"2025082711453117000_15.11.e250852.2","doi-asserted-by":"crossref","first-page":"ofz399","DOI":"10.1093\/ofid\/ofz399","article-title":"Invasive Ureaplasma Infection in Patients Receiving Rituximab and Other Humoral Immunodeficiencies-A Case Report and Review of the Literature","volume":"6","author":"Jhaveri","year":"2019","journal-title":"Open Forum Infect Dis"},{"key":"2025082711453117000_15.11.e250852.3","doi-asserted-by":"crossref","first-page":"117954842096623","DOI":"10.1177\/1179548420966234","article-title":"Hyperammonemia post lung transplantation: a review","volume":"14","author":"Leger","year":"2020","journal-title":"Clin Med Insights Circ Respir Pulm 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Oncol"},{"key":"2025082711453117000_15.11.e250852.11","doi-asserted-by":"crossref","DOI":"10.1093\/ofid\/ofz033","article-title":"Two Cases of Fatal Hyperammonemia Syndrome due to Mycoplasma hominis and Ureaplasma urealyticum in Immunocompromised Patients Outside Lung Transplant Recipients","volume":"6","author":"Nowbakht","year":"2019","journal-title":"Open Forum Infect Dis"},{"key":"2025082711453117000_15.11.e250852.12","doi-asserted-by":"publisher","DOI":"10.1111\/tid.12839"},{"key":"2025082711453117000_15.11.e250852.13","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2021-242513","article-title":"Lethal hyperammonemia in a CAR-T cell recipient due to Ureaplasma pneumonia: a case report of a unique severe complication","volume":"14","author":"Tawfik","year":"2021","journal-title":"BMJ Case Rep"},{"key":"2025082711453117000_15.11.e250852.14","doi-asserted-by":"crossref","DOI":"10.1111\/tid.13328","article-title":"Hyperammonemia syndrome due to Ureaplasma urealyticum in a kidney transplant recipient: a case of disseminated disease from a fluoroquinolone-resistant isolate","volume":"22","author":"Higgins","year":"2020","journal-title":"Transpl Infect Dis"},{"key":"2025082711453117000_15.11.e250852.15","doi-asserted-by":"crossref","DOI":"10.1111\/tid.13298","article-title":"Hyperammonemia syndrome due to Ureaplasma infection after liver-kidney transplant","volume":"22","author":"Cannon","year":"2020","journal-title":"Transpl Infect Dis"},{"key":"2025082711453117000_15.11.e250852.16","doi-asserted-by":"crossref","DOI":"10.1111\/tid.13332","article-title":"Successful management of noncirrhotic hyperammonemia syndrome after kidney transplantation from putative Ureaplasma infection","volume":"22","author":"Cheema","year":"2020","journal-title":"Transpl Infect Dis"},{"key":"2025082711453117000_15.11.e250852.17","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.jcrc.2020.02.003","article-title":"Ureaplasma parvum causes hyperammonemia presenting as refractory status epilepticus after kidney transplant","volume":"57","author":"Legouy","year":"2020","journal-title":"J Crit Care"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2022-250852","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T18:45:37Z","timestamp":1756320337000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2022-250852"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11]]},"references-count":17,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2022,11,9]]},"published-print":{"date-parts":[[2022,11]]}},"alternative-id":["10.1136\/bcr-2022-250852"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2022-250852","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,11]]}}}