{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T06:10:07Z","timestamp":1756361407778,"version":"3.44.0"},"reference-count":16,"publisher":"BMJ","issue":"12","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2022,11,21]]},"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:p>A woman in her 70s presented with a small subcutaneous retrosacrococcygeal mass and a history of elevated erythrocyte sedimentation rate present for several years. It was misdiagnosed as an inflammatory process of unclear origin. She underwent further investigation with the appearance of weight loss and weakness. A sacrococcygeal mass was noted on CT scan. A core needle biopsy was inconclusive for chordoma versus myoepithelioma. Wide surgical resection of the tumour including the coccygeal bone was performed. Following surgery, all the systemic symptoms resolved with normalisation of inflammatory markers. The pathological examination showed a relatively circumscribed multinodular myxoid tumour with lymphatic tissue cuff. Pan-sarcoma fusion analysis detected an EWSR1 (Exon7)-CREB1 (Exon7) fusion gene. The lesion was diagnosed as angiomatoid fibrous histiocytoma with paraneoplastic syndrome presentation of several years\u2019 duration.<\/jats:p>","DOI":"10.1136\/bcr-2022-250946","type":"journal-article","created":{"date-parts":[[2022,12,7]],"date-time":"2022-12-07T10:30:44Z","timestamp":1670409044000},"page":"e250946","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Paraneoplastic syndrome due to angiomatoid fibrous histiocytoma: a known presentation of an uncommon diagnosis in a rare site and age"],"prefix":"10.1136","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7045-680X","authenticated-orcid":false,"given":"Omer","family":"Or","sequence":"first","affiliation":[{"name":"Department of Orthopedics, Hadassah University Medical Hospital, Jerusalem, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noam","family":"Olshinka","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Hadassah University Medical Hospital, Jerusalem, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noam","family":"Shussman","sequence":"additional","affiliation":[{"name":"Department of Surgery, Hadassah University Medical Center, Jerusalem, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judith","family":"Diment","sequence":"additional","affiliation":[{"name":"Department of Pathology, Hadassah University Medical Center, Jerusalem, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2022,12,7]]},"reference":[{"key":"2025082722414692000_15.12.e250946.1","doi-asserted-by":"crossref","first-page":"674","DOI":"10.5858\/arpa.2014-0234-RA","article-title":"Angiomatoid fibrous histiocytoma: the current status of pathology and genetics","volume":"139","author":"Thway","year":"2015","journal-title":"Arch Pathol Lab Med"},{"key":"2025082722414692000_15.12.e250946.2","doi-asserted-by":"crossref","first-page":"343","DOI":"10.4103\/0973-1482.119297","article-title":"Sacrococcygeal neoplastic lesions","volume":"9","author":"Lianos","year":"2013","journal-title":"J Cancer Res Ther"},{"key":"2025082722414692000_15.12.e250946.3","doi-asserted-by":"crossref","first-page":"1520","DOI":"10.1016\/j.ejso.2019.05.003","article-title":"Myoepithelioma of the soft tissue: a systematic review of clinical reports","volume":"45","author":"Rastrelli","year":"2019","journal-title":"European Journal of Surgical Oncology"},{"key":"2025082722414692000_15.12.e250946.4","doi-asserted-by":"crossref","unstructured":"Court C , Briand S , Mir O . 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