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Subsequent Cosyntropin stimulation showed primary adrenal insufficiency and adrenal CT demonstrated large infiltrative masses. Adrenal biopsy confirmed the diagnosis of primary adrenal lymphoma of the B-cell type. This case demonstrates the importance of including lymphoma in the differential diagnosis of adrenal insufficiency, particularly in the elderly population and in the setting of negative 21-hydroxlyase antibody results.<\/jats:p>","DOI":"10.1136\/bcr-2022-250973","type":"journal-article","created":{"date-parts":[[2022,9,27]],"date-time":"2022-09-27T12:53:36Z","timestamp":1664283216000},"page":"e250973","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Primary adrenal insufficiency masking as an adrenal B-cell lymphoma"],"prefix":"10.1136","volume":"15","author":[{"given":"Eric","family":"Kuhn","sequence":"first","affiliation":[{"name":"Endocrinology, Walter Reed National Military Medical Center, Bethesda, Maryland, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John R","family":"Sanchez","sequence":"additional","affiliation":[{"name":"Pathology, Walter Reed National Military Medical Center, 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