{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T16:21:50Z","timestamp":1790266910507,"version":"4.1.0"},"reference-count":35,"publisher":"BMJ","issue":"11","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2022,11,14]]},"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:p>Aspergillus osteomyelitis (AO) is a rare and often lethal opportunistic infection in predominantly immunocompromised patients. Treatment has shifted from amphotericin therapy to voriconazole monotherapy due to increased effectiveness and less toxicity. We report a case of an immunocompetent woman with vertebral osteomyelitis due to <jats:italic>Aspergillus flavus<\/jats:italic> who was successfully treated with surgery (requiring hardware implantation) and monotherapy posaconazole (following intolerance and hepatitis due to voriconazole). She remained well at follow-up post cessation of 12 months of antifungal therapy. We provide an updated literature review examining the role of azole monotherapy as the gold standard of treatment for AO.<\/jats:p>","DOI":"10.1136\/bcr-2022-251101","type":"journal-article","created":{"date-parts":[[2022,11,22]],"date-time":"2022-11-22T10:40:49Z","timestamp":1669113649000},"page":"e251101","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Successful treatment of vertebral osteomyelitis due to <i>Aspergillus flavus<\/i> in an immunocompetent patient"],"prefix":"10.1136","volume":"15","author":[{"given":"Myong Gyu Joshua","family":"Kim","sequence":"first","affiliation":[{"name":"University of New South Wales, Prince of Wales Clinical School, Randwick, New South Wales, Australia"},{"name":"Infectious Diseases, Prince of Wales Hospital and Community Health Services, Randwick, New South Wales, 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