{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T12:20:00Z","timestamp":1784204400746,"version":"3.55.0"},"reference-count":23,"publisher":"BMJ","issue":"5","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2023,4,21]]},"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:p>As COVID-19 vaccination becomes widely available and administered globally, there have been several reports of side effects attributed to the vaccine. This report highlights a patient who developed stroke 2\u2009days following the administration of the COVID-19 vaccine, although its association remains uncertain. A man in his late 30s developed acute neurological symptoms 2\u2009days after receiving the booster dose of the BNT162b2 (Pfizer-BioNTech) mRNA COVID-19 vaccine. History and neurological examination suggested a posterior circulation stroke, which was confirmed by MRI, as a right-sided posterior inferior cerebellar artery stroke. Full workup did not suggest other causes of the stroke. Due to the patient\u2019s age and well-controlled risk factors, it was presumed to be a rare adverse effect of the vaccine. Medical management with aspirin, statin therapy and rehabilitation led to the improvement of symptoms and enabled ongoing restoration of function. Further cases of stroke following administration of COVID-19 vaccine have been documented in the literature, but the association is yet to be established.<\/jats:p>","DOI":"10.1136\/bcr-2022-251180","type":"journal-article","created":{"date-parts":[[2023,5,5]],"date-time":"2023-05-05T10:15:15Z","timestamp":1683281715000},"page":"e251180","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Cerebellar and brainstem stroke possibly associated with booster dose of BNT162b2 (Pfizer-BioNTech) COVID-19 vaccine"],"prefix":"10.1136","volume":"16","author":[{"given":"Michael George","family":"Thomas","sequence":"first","affiliation":[{"name":"Acute Medical Unit, Royal Perth Hospital, Perth, Western Australia, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0172-7872","authenticated-orcid":false,"given":"Andrew","family":"Dermawan","sequence":"additional","affiliation":[{"name":"Gastroenterology, Royal Perth Hospital, Perth, Western Australia, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sue","family":"Teh","sequence":"additional","affiliation":[{"name":"Acute Medical Unit, Royal Perth Hospital, Perth, Western Australia, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2023,5,5]]},"reference":[{"key":"2025082709025251000_16.5.e251180.1","unstructured":"Therapeutic Goods Administration Australia . 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COVID-19 vaccination \u2013 vaccination data \u2013 19 March 2022 [Australian Government Department of Health]. 2022. Available: https:\/\/www.health.gov.au\/resources\/publications\/covid-19-vaccination-vaccination-data-19-march-2022 [Accessed 20 Mar 2022]."},{"key":"2025082709025251000_16.5.e251180.14","unstructured":"World Health Organisation . The moderna COVID-19 (mrna-1273) vaccine: what you need to know. 2022. Available: https:\/\/www.who.int\/news-room\/feature-stories\/detail\/the-moderna-covid-19-mrna-1273-vaccine-what-you-need-to-know [Accessed 20 Mar 2022]."},{"key":"2025082709025251000_16.5.e251180.15","unstructured":"Therapeutic Goods Administration Australia . COMIRNATY original\/omicron BA.4-5 COVID-19 vaccine. 2023. Available: https:\/\/www.ebs.tga.gov.au\/ebs\/picmi\/picmirepository.nsf\/pdf?OpenAgent=&id=CP-2023-PI-01101-1&d=20230318172310101 [Accessed 18 Mar 2023]."},{"key":"2025082709025251000_16.5.e251180.16","unstructured":"Medicines.org.au . Australian product information \u2013 COMIRNATY (bnt162b2 [ mRNA ]) COVID-19 vaccine. 2022. Available: http:\/\/medicines.org.au\/i\/view\/pfpcoviiPI [Accessed 20 Mar 2022]."},{"key":"2025082709025251000_16.5.e251180.17","doi-asserted-by":"publisher","DOI":"10.1177\/1747493020972922"},{"key":"2025082709025251000_16.5.e251180.18","doi-asserted-by":"publisher","DOI":"10.1177\/17474930211005373"},{"key":"2025082709025251000_16.5.e251180.19","unstructured":"Therapeutic Guidelines Limited . Stroke and transient ischaemic attack. 2019. Available: https:\/\/tgldcdp-tg-org-au.eu1.proxy.openathens.net\/viewTopic?etgAccess=true&guidelinePage=Neurology&topicfile=stroke-and-transient-ischaemic-attack&guidelinename=Neurology\u00a7ionId=toc_d1e175#toc_d1e175 [Accessed 20 Mar 2022]."},{"key":"2025082709025251000_16.5.e251180.20","unstructured":"Bloomberg News . Pfizer bivalent vaccine linked to strokes in preliminary data. 2023. 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