{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T11:10:16Z","timestamp":1756293016834,"version":"3.44.0"},"reference-count":10,"publisher":"BMJ","issue":"4","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2023,4,6]]},"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:p>Lymphangioleiomyomatosis (LAM) is characterised by the proliferation of abnormal smooth muscle cells (LAM cells) in the lungs, lymph nodes and other organs. We report the case of a man in his 50s who had right-sided pleural effusion. On performing a diagnostic tap, the fluid was milky white in colour. An intercostal chest tube was inserted and after complete drainage of fluid, a high-resolution CT (HRCT) was done. HRCT revealed multiple cysts throughout both of the lungs. On subsequent bronchoscopy-guided transbronchial lung biopsy and histochemical staining, diagnosis of LAM was made. We started the patient on oral sirolimus. On subsequent follow-up, subjective and objective improvements were observed.<\/jats:p>","DOI":"10.1136\/bcr-2022-251513","type":"journal-article","created":{"date-parts":[[2023,4,19]],"date-time":"2023-04-19T10:41:05Z","timestamp":1681900865000},"page":"e251513","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Cystic lung disease lymphangioleiomyomatosis (LAM) in a male patient"],"prefix":"10.1136","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2253-1518","authenticated-orcid":false,"given":"Ashish Kumar","family":"Prakash","sequence":"first","affiliation":[{"name":"Respiratory and Sleep Medicine, Medanta\u2013The Medicity, Gurgaon, Haryana, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siddharth","family":"Chatterjee","sequence":"additional","affiliation":[{"name":"Respiratory and Sleep Medicine, Medanta\u2013The Medicity, Gurgaon, Haryana, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bornali","family":"Datta","sequence":"additional","affiliation":[{"name":"Respiratory and Sleep Medicine, Medanta\u2013The Medicity, Gurgaon, Haryana, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anand","family":"Jaiswal","sequence":"additional","affiliation":[{"name":"Respiratory and Sleep Medicine, Medanta\u2013The Medicity, Gurgaon, Haryana, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2023,4,19]]},"reference":[{"key":"2025082703454405000_16.4.e251513.1","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1177\/107327480601300405","article-title":"Lymphangioleiomyomatosis","volume":"13","author":"Taveira-DaSilva","year":"2006","journal-title":"Cancer Control"},{"key":"2025082703454405000_16.4.e251513.2","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.162.2.9911006"},{"key":"2025082703454405000_16.4.e251513.3","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2012.07.007"},{"key":"2025082703454405000_16.4.e251513.4","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200409-1298OC"},{"key":"2025082703454405000_16.4.e251513.5","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.06.00113303"},{"key":"2025082703454405000_16.4.e251513.6","doi-asserted-by":"publisher","DOI":"10.1378\/chest.123.2.623"},{"key":"2025082703454405000_16.4.e251513.7","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199311000-00002"},{"key":"2025082703454405000_16.4.e251513.8","doi-asserted-by":"crossref","first-page":"154","DOI":"10.4103\/lungindia.lungindia_526_20","article-title":"Chylothorax-modalities of management and outcomes: a case series","volume":"38","author":"Pulle","year":"2021","journal-title":"Lung India"},{"key":"2025082703454405000_16.4.e251513.9","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1100391"},{"key":"2025082703454405000_16.4.e251513.10","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2010.09.026"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2022-251513","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T10:45:55Z","timestamp":1756291555000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2022-251513"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4]]},"references-count":10,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2023,4,19]]},"published-print":{"date-parts":[[2023,4]]}},"alternative-id":["10.1136\/bcr-2022-251513"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2022-251513","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2023,4]]}}}