{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T16:15:18Z","timestamp":1787501718330,"version":"build-2736575974"},"reference-count":11,"publisher":"BMJ","issue":"10","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2023,9,23]]},"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:p>Pentalogy of Fallot is a rare congenital cyanotic heart disease; few patients with uncorrected disease survive to childbearing age. Cardiovascular changes during pregnancy and delivery can lead to haemodynamic instability, while anaesthesia can cause right-to-left shunting and worsen hypoxaemia.<\/jats:p>\n                  <jats:p>We present the learning points from the anaesthetic management of an obstetric patient with uncorrected pentalogy of Fallot. We describe the successful application of general anaesthesia, choice of transoesophageal echocardiography for real-time haemodynamic monitoring and management, and the comprehensive multidisciplinary care of this high cardiovascular risk obstetric patient perioperatively. We also review the literature and discuss the anaesthetic management of patients with pentalogy of Fallot going for caesarean section.<\/jats:p>","DOI":"10.1136\/bcr-2022-251598","type":"journal-article","created":{"date-parts":[[2024,2,7]],"date-time":"2024-02-07T11:50:07Z","timestamp":1707306607000},"page":"e251598","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Anaesthesia of a parturient with uncorrected pentalogy of Fallot undergoing caesarean section and postpartum sterilisation"],"prefix":"10.1136","volume":"16","author":[{"given":"Rachel Wei-Li","family":"Leong","sequence":"first","affiliation":[{"name":"Anaesthesia and Surgical Intensive Care, Singapore General Hospital, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2769-1089","authenticated-orcid":false,"given":"Jinghui","family":"Chen","sequence":"additional","affiliation":[{"name":"Anaesthesia and Surgical Intensive Care, Singapore General Hospital, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abey Matthew Varughese","family":"Mathews","sequence":"additional","affiliation":[{"name":"Anaesthesia and Surgical Intensive Care, Singapore General Hospital, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harikrishnan","family":"Kothandan","sequence":"additional","affiliation":[{"name":"Anaesthesia, Singhealth, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2023,10,6]]},"reference":[{"key":"2025082712413011000_16.10.e251598.1","unstructured":"Misirlio\u011flu ED , Alpan N . Pentalogy of Fallot. In: Lang F , ed. Encyclopedia of molecular mechanisms of disease. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009: 1602\u20135."},{"key":"2025082712413011000_16.10.e251598.2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(78)90941-4"},{"key":"2025082712413011000_16.10.e251598.3","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/S1701-2163(16)35492-5","article-title":"Congenital heart disease in pregnancy","volume":"29","author":"Davies","year":"2007","journal-title":"J Obstet Gynaecol Can"},{"key":"2025082712413011000_16.10.e251598.4","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2016-216809","article-title":"Multiple pregnancy in a primigravida with uncorrected Pentalogy of Fallot","volume":"2017","author":"Partana","year":"2017","journal-title":"BMJ Case Rep"},{"key":"2025082712413011000_16.10.e251598.5","doi-asserted-by":"crossref","first-page":"267","DOI":"10.4103\/aer.AER_126_17","article-title":"An unusual case of a parturient with uncorrected Pentalogy of Fallot presenting for elective cesarean section delivery of twins","volume":"12","author":"Ho","year":"2018","journal-title":"Anesth Essays Res"},{"key":"2025082712413011000_16.10.e251598.6","doi-asserted-by":"crossref","first-page":"186","DOI":"10.4103\/0019-5049.96336","article-title":"Labour analgesia and anaesthetic management of a primigravida with uncorrected Pentology of Fallot","volume":"56","author":"Sandhya","year":"2012","journal-title":"Indian J Anaesth"},{"key":"2025082712413011000_16.10.e251598.7","doi-asserted-by":"crossref","unstructured":"van der Ven JPG , van den Bosch E , Bogers A , et al . Current outcomes and treatment of Tetralogy of Fallot. F1000Res 2019;8. doi:10.12688\/f1000research.17174.1","DOI":"10.12688\/f1000research.17174.1"},{"key":"2025082712413011000_16.10.e251598.8","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehy340"},{"key":"2025082712413011000_16.10.e251598.9","doi-asserted-by":"crossref","first-page":"47","DOI":"10.4103\/2249-4472.99325","article-title":"Central neuraxial anesthesia for caesarean section in parturients with uncorrected Tetralogy of Fallot: two cases","volume":"2","author":"Baidya","year":"2012","journal-title":"J Obstet Anaesth Crit Care"},{"key":"2025082712413011000_16.10.e251598.10","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0b013e3181ae51a6"},{"key":"2025082712413011000_16.10.e251598.11","unstructured":"National Guideline Alliance (UK) . (NICE guideline, no. 121.) Intrapartum care for women with cardiac disease \u2013 management of the third stage of labour. Intrapartum care for women with existing medical conditions or obstetric complications and their babies. London National Institute for Health and Care Excellence (UK); 2019."}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2022-251598","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T19:41:39Z","timestamp":1756323699000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2022-251598"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10]]},"references-count":11,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2023,10,6]]},"published-print":{"date-parts":[[2023,10]]}},"alternative-id":["10.1136\/bcr-2022-251598"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2022-251598","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10]]}}}