{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T06:10:04Z","timestamp":1756361404366,"version":"3.44.0"},"reference-count":14,"publisher":"BMJ","issue":"1","license":[{"start":{"date-parts":[[2023,1,3]],"date-time":"2023-01-03T00:00:00Z","timestamp":1672704000000},"content-version":"unspecified","delay-in-days":2,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2022,12,1]]},"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:p>Hyperkalemic periodic paralysis (HyperKPP) is a rare disease with significant anaesthetic implications. We compare two perioperative courses in the same patient. The first surgery resulted in paralysis and a protracted hospitalisation, while the second surgery resulted in a same-day discharge. Various anaesthetic techniques may be used; however, clear communication surrounding optimisation both for home medications (eg, continuing potassium wasting diuretics) and avoidance of triggering medications (primarily: depolarising neuromuscular blockers), along with thermoregulation and glucose management plans, is critical and best performed early by an anaesthetic precare clinic. Our cases highlight the physiological underpinnings in managing patients with HyperKPP.<\/jats:p>","DOI":"10.1136\/bcr-2022-251699","type":"journal-article","created":{"date-parts":[[2023,1,3]],"date-time":"2023-01-03T11:51:26Z","timestamp":1672746686000},"page":"e251699","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Hyperkalemic periodic paralysis with paramyotonia and the anaesthetic implications"],"prefix":"10.1136","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1233-2358","authenticated-orcid":false,"given":"David","family":"Sender","sequence":"first","affiliation":[{"name":"Anesthesiology, The University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"Doyal","sequence":"additional","affiliation":[{"name":"Anesthesiology, The University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2023,1,3]]},"reference":[{"key":"2025082722392611000_16.1.e251699.1","doi-asserted-by":"publisher","DOI":"10.1016\/0896-6273(93)90168-Q"},{"key":"2025082722392611000_16.1.e251699.2","doi-asserted-by":"publisher","DOI":"10.1016\/j.nurt.2007.02.001"},{"key":"2025082722392611000_16.1.e251699.3","first-page":"40","article-title":"Hyperkalemia revisited","volume":"33","author":"Parham","year":"2006","journal-title":"Tex Heart Inst J"},{"key":"2025082722392611000_16.1.e251699.4","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCEP.116.004667","article-title":"Electrophysiology of hypokalemia and hyperkalemia","volume":"10","author":"Weiss","year":"2017","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"2025082722392611000_16.1.e251699.5","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-013-7025-9"},{"key":"2025082722392611000_16.1.e251699.6","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1152\/physrev.1999.79.4.1317","article-title":"Voltage-Gated ion channels and hereditary disease","volume":"79","author":"Lehmann-Horn","year":"1999","journal-title":"Physiol Rev"},{"key":"2025082722392611000_16.1.e251699.7","first-page":"347","article-title":"Hyperkalemic periodic paralysis: 14 years later","volume":"52","author":"Spier","year":"2006","journal-title":"AAEP Proceedings"},{"key":"2025082722392611000_16.1.e251699.8","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1007\/BF03018562","article-title":"Epidural anesthesia in a patient with hyperkalemic periodic paralysis undergoing orthopedic surgery","volume":"51","author":"Aouad","year":"2004","journal-title":"Can J Anaesth"},{"key":"2025082722392611000_16.1.e251699.9","first-page":"425","article-title":"Extreme intraoperative hyperkalemia in a nondialysis patient undergoing kidney transplantation","volume":"21","author":"Kazanjian","year":"2011","journal-title":"\u202fMiddle East J Anesthesiol"},{"key":"2025082722392611000_16.1.e251699.10","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2017-223588","article-title":"Hyperkalaemic periodic paralysis in pregnancy","volume":"2018","author":"Yong","year":"2018","journal-title":"BMJ Case Rep"},{"key":"2025082722392611000_16.1.e251699.11","unstructured":"Weber F . Hyperkalemic Periodic Paralysis. In: Adam MP , Ardinger HH , Pagon RA , eds. GeneReviews\u00ae. Seattle, WA: University of Washington, 2021. https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK1496\/"},{"key":"2025082722392611000_16.1.e251699.12","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0b013e31817f6d76"},{"key":"2025082722392611000_16.1.e251699.13","doi-asserted-by":"crossref","first-page":"302","DOI":"10.4103\/0971-9784.101867","article-title":"Management of a patient with hyperkalemic periodic paralysis requiring coronary artery bypass grafts","volume":"15","author":"Patangi","year":"2012","journal-title":"Ann Card Anaesth"},{"key":"2025082722392611000_16.1.e251699.14","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/72.2.210"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2022-251699","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T05:39:33Z","timestamp":1756359573000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2022-251699"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":14,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2023,1,3]]},"published-print":{"date-parts":[[2023,1]]}},"alternative-id":["10.1136\/bcr-2022-251699"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2022-251699","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2023,1]]}}}