{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T17:19:51Z","timestamp":1780593591796,"version":"3.54.1"},"reference-count":7,"publisher":"BMJ","issue":"9","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2022,9,17]]},"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:p>Primary ovarian leiomyosarcoma is a very uncommon and aggressive neoplasm. We presented a right-sided ovarian leiomyosarcoma in a woman in her late 40s. No case has been described in the literature till now of primary ovarian leiomyosarcoma in a woman with uterovaginal prolapse. A total abdominal hysterectomy with bilateral adnexectomy, metastasectomy, excision of large tumour deposit over small intestine followed by resection with ileo-ileal anastomosis and omentectomy was performed. The diagnosis was made based on morphology along with immunohistochemistry. The patient was given adjuvant chemotherapy during postoperative period. Due to rarity, there is a dearth of information on the clinical behaviour and best treatment options for these tumours. This case report highlighted the importance of clinical awareness and aimed to provide a baseline to guide clinical practice as well as future research.<\/jats:p>","DOI":"10.1136\/bcr-2022-251733","type":"journal-article","created":{"date-parts":[[2022,9,26]],"date-time":"2022-09-26T12:35:40Z","timestamp":1664195740000},"page":"e251733","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Primary ovarian leiomyosarcoma in a woman with uterovaginal prolapse"],"prefix":"10.1136","volume":"15","author":[{"given":"Anupama","family":"Bahadur","sequence":"first","affiliation":[{"name":"Obstetrics and Gynaecology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3359-2239","authenticated-orcid":false,"given":"Rajlaxmi","family":"Mundhra","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynaecology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7888-4251","authenticated-orcid":false,"given":"Pallavi","family":"Verma","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynaecology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ravi Hari","family":"Phulware","sequence":"additional","affiliation":[{"name":"Pathology and Laboratory Medicine, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2022,9,26]]},"reference":[{"key":"2025082803554347000_15.9.e251733.1","first-page":"87","volume-title":"Female genital tumours: who classification of tumours","volume":"4","year":"2020"},{"key":"2025082803554347000_15.9.e251733.2","doi-asserted-by":"crossref","first-page":"100737","DOI":"10.1016\/j.gore.2021.100737","article-title":"Clinical management and outcomes of primary ovarian leiomyosarcoma - Experience from a sarcoma specialist unit","volume":"36","author":"Cojocaru","year":"2021","journal-title":"Gynecol Oncol Rep"},{"key":"2025082803554347000_15.9.e251733.3","doi-asserted-by":"crossref","first-page":"26","DOI":"10.14740\/jcgo477w","article-title":"Case report of a primary ovarian leiomyosarcoma diagnosed by h-caldesmon staining","volume":"7","author":"Tanaka","year":"2018","journal-title":"J Clin Gynecol Obstet"},{"key":"2025082803554347000_15.9.e251733.4","first-page":"941","article-title":"Primary ovarian leiomyosarcoma. An immunohistochemical and ultrastructural study","volume":"115","author":"Friedman","year":"1991","journal-title":"Arch Pathol Lab Med"},{"key":"2025082803554347000_15.9.e251733.5","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1097\/01.ogx.0000268629.16151.71","article-title":"Primary ovarian leiomyosarcoma: a review of the clinical and immunohistochemical features of the rare tumor","volume":"62","author":"Ta\u015fkin","year":"2007","journal-title":"Obstet Gynecol Surv"},{"key":"2025082803554347000_15.9.e251733.6","doi-asserted-by":"publisher","DOI":"10.1097\/01.pas.0000141393.99300.d0"},{"key":"2025082803554347000_15.9.e251733.7","doi-asserted-by":"publisher","DOI":"10.1097\/IGC.0000000000000261"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2022-251733","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T10:55:55Z","timestamp":1756378555000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2022-251733"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9]]},"references-count":7,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2022,9,26]]},"published-print":{"date-parts":[[2022,9]]}},"alternative-id":["10.1136\/bcr-2022-251733"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2022-251733","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9]]}}}