{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T16:10:05Z","timestamp":1756311005004,"version":"3.44.0"},"reference-count":15,"publisher":"BMJ","issue":"1","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2022,12,29]]},"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:p>\n                  <jats:italic>Escherichia coli<\/jats:italic> is a rare cause of community-acquired meningitis comprising about 1% of adult cases. However, it is a common pathogen in neonatal meningitis and in nosocomial setting (especially after penetrating craniocerebral injury or subsequent to neurosurgical procedures). We report a middle-aged woman, who was admitted with features of acute meningitis and subsequent investigations revealed <jats:italic>E. coli<\/jats:italic> growth in cerebrospinal fluid culture. The case is distinctive as no additional predisposing risk factors associated with gram-negative bacillary meningitis (traumatic brain injury, neurosurgical procedures, malignancy, immunosuppressive therapy, HIV infection, chronic alcoholism and diabetes) were present. She was treated with intravenous antibiotics as per sensitivity reports and discharged in clinically stable condition, without any residual neurological deficit.<\/jats:p>","DOI":"10.1136\/bcr-2022-251850","type":"journal-article","created":{"date-parts":[[2023,1,10]],"date-time":"2023-01-10T10:05:57Z","timestamp":1673345157000},"page":"e251850","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Gram-negative bacillary meningitis in an immunocompetent adult"],"prefix":"10.1136","volume":"16","author":[{"given":"Aniruddha","family":"Ray","sequence":"first","affiliation":[{"name":"Internal Medicine, RG Kar Medical College and Hospital, Kolkata, West Bengal, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satyaki","family":"Basu","sequence":"additional","affiliation":[{"name":"Internal Medicine, RG Kar Medical College and Hospital, Kolkata, West Bengal, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Souradeep","family":"Das","sequence":"additional","affiliation":[{"name":"Internal Medicine, RG Kar Medical College and Hospital, Kolkata, West Bengal, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3809-8926","authenticated-orcid":false,"given":"Atanu","family":"Chandra","sequence":"additional","affiliation":[{"name":"Internal Medicine, RG Kar Medical College and Hospital, Kolkata, West Bengal, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2023,1,10]]},"reference":[{"key":"2025082708503619000_16.1.e251850.1","doi-asserted-by":"publisher","DOI":"10.1177\/1756285609337975"},{"key":"2025082708503619000_16.1.e251850.2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2008.02193.x"},{"key":"2025082708503619000_16.1.e251850.3","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00070-09"},{"key":"2025082708503619000_16.1.e251850.4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1005384"},{"key":"2025082708503619000_16.1.e251850.5","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa040845"},{"key":"2025082708503619000_16.1.e251850.6","doi-asserted-by":"crossref","DOI":"10.1186\/s12879-015-1310-4","article-title":"Community-Acquired adult Escherichia coli meningitis leading to diagnosis of unrecognized retropharyngeal abscess and cervical spondylodiscitis: a case report","volume":"15","author":"Kohlmann","year":"2015","journal-title":"BMC Infect Dis"},{"key":"2025082708503619000_16.1.e251850.7","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1080\/20009666.2020.1715190","article-title":"Escherichia coli: a rare cause of meningitis in immuno-competent adult","volume":"10","author":"Zafar","year":"2020","journal-title":"J Community Hosp Intern Med Perspect"},{"key":"2025082708503619000_16.1.e251850.8","unstructured":"Roos KL , Tyler KL . 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