{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T00:04:28Z","timestamp":1756425868349,"version":"3.44.0"},"reference-count":26,"publisher":"BMJ","issue":"12","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2022,12,2]]},"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:p>Inferior mesenteric vein thrombosis (IMVT) is a rare and potentially lethal complication that can progress to mesenteric ischaemia if left untreated. We report a case of a man in his 70s with a history of polycythaemia vera (PV) with a known negative Janus kinase-2 mutation (<jats:italic>JAK2V617<\/jats:italic>) who was started on testosterone therapy 2 months before presenting with left lower quadrant abdominal and flank pain. Evaluation revealed thrombocytosis and IMVT on CT scan. A non-operative approach was deferred for anticoagulation therapy. Within 24\u2009hours, the patient demonstrated significant clinical improvement, and he subsequently made a full recovery. The patient underwent 6\u2009months of anticoagulation therapy with Apixaban. This case documents the first case of IMVT in the setting of PV and testosterone therapy in the literature.<\/jats:p>","DOI":"10.1136\/bcr-2022-251886","type":"journal-article","created":{"date-parts":[[2022,12,14]],"date-time":"2022-12-14T09:55:18Z","timestamp":1671011718000},"page":"e251886","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Inferior mesenteric vein thrombosis in the setting of testosterone therapy"],"prefix":"10.1136","volume":"15","author":[{"given":"Ngoda","family":"Manongi","sequence":"first","affiliation":[{"name":"Internal Medicine, NewYork-Presbyterian Queens, Flushing, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kory","family":"Byrns","sequence":"additional","affiliation":[{"name":"Internal Medicine, NewYork-Presbyterian Queens, Flushing, New York, 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