{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T17:40:03Z","timestamp":1756316403641,"version":"3.44.0"},"reference-count":19,"publisher":"BMJ","issue":"11","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2022,11,16]]},"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:p>Ankylosing spondylosis (AS) is characterised by bilateral sacroiliitis, asymmetric peripheral oligoarthritis, association with the human leucocyte antigen-B27, enthesitis and dactylitis. The association of IgA vasculitis with AS has been documented in few case reports. We present a rare case of a man in his 40s with AS, who presented with fever, bloody loose stools, abdominal pain, lower limb arthritis, palpable purpura over the lower limbs. He subsequently, also developed renal involvement in the form of proteinuria. His skin biopsy showed evidence of leucocytoclastic vasculitis, while renal biopsy showed focal proliferative, necrotising IgA glomerulonephritis. He was thus diagnosed to have Henoch Schonlein purpura with IgA nephropathy in the background of AS. He was treated with steroids and mycophenolate mofetil with resolution of his symptoms.<\/jats:p>","DOI":"10.1136\/bcr-2022-252182","type":"journal-article","created":{"date-parts":[[2022,11,24]],"date-time":"2022-11-24T12:11:08Z","timestamp":1669291868000},"page":"e252182","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":7,"title":["Rare case of ankylosing spondylitis complicated by IgA vasculitis"],"prefix":"10.1136","volume":"15","author":[{"given":"Sangita","family":"Kamath","sequence":"first","affiliation":[{"name":"Department of Medicine, Tata Main Hospital, Jamshedpur, Jharkhand, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0625-9243","authenticated-orcid":false,"given":"Tauheed","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Department of Medicine, Tata Main Hospital, Jamshedpur, Jharkhand, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Farah","family":"Rana","sequence":"additional","affiliation":[{"name":"Department of Pathology, Tata Main Hospital, Jamshedpur, Jharkhand, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ajat Shatru","family":"Upadhyay","sequence":"additional","affiliation":[{"name":"Department of Medicine, Tata Main Hospital, Jamshedpur, Jharkhand, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2022,11,24]]},"reference":[{"key":"2025082710082658000_15.11.e252182.1","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2018-228881","article-title":"Henoch-schonlein purpura associated with HLA-B27 positive axial spondyloarthritis in a young man","volume":"12","author":"John","year":"2019","journal-title":"BMJ Case Rep"},{"key":"2025082710082658000_15.11.e252182.2","first-page":"1","article-title":"Leukocytoclastic vasculitis in a patient with ankylosing spondylitis","volume":"2014","author":"Kobak","year":"2014","journal-title":"Case Rep Rheumatol"},{"key":"2025082710082658000_15.11.e252182.3","doi-asserted-by":"publisher","DOI":"10.1136\/ard.52.1.61"},{"key":"2025082710082658000_15.11.e252182.4","doi-asserted-by":"crossref","DOI":"10.2340\/0001555577324","article-title":"Cutaneous leukocytoclastic vasculitis in a case of ankylosing spondylitis","volume":"77","author":"Machet","year":"1997","journal-title":"Acta Derm Venereol"},{"key":"2025082710082658000_15.11.e252182.5","first-page":"83","article-title":"Coexisting IgA nephropathy and leukocytoclastic cutaneous vasculitis associated with ankylosing spondylitis: a case report","volume":"55","author":"Hsu","year":"1995","journal-title":"Zhonghua Yi Xue Za Zhi"},{"key":"2025082710082658000_15.11.e252182.6","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2015-208174"},{"key":"2025082710082658000_15.11.e252182.7","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1159\/000181975","article-title":"A renal lesion in ankylosing spondylitis","volume":"26","author":"Bailey","year":"1980","journal-title":"Nephron"},{"key":"2025082710082658000_15.11.e252182.8","doi-asserted-by":"publisher","DOI":"10.1136\/ard.39.6.545"},{"key":"2025082710082658000_15.11.e252182.9","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1159\/000185082","article-title":"Immunoglobulin nephropathy and ankylosing spondylitis. 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