{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T11:40:04Z","timestamp":1756294804469,"version":"3.44.0"},"reference-count":14,"publisher":"BMJ","issue":"12","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2023,11,29]]},"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:p>Buerger\u2019s disease (BD), also known as thromboangiitis obliterans, is a non-atherosclerotic inflammatory disorder of unknown aetiology that affects small-sized and medium-sized vessels of the extremities. It is usually observed in middle-aged adults, especially those who smoke or use tobacco products. This condition is more frequently observed in men, although recent findings indicate an increasing prevalence among women, potentially due to increased cigarette use. The association between pregnancy and BD is rare, with only a few published cases. Previous reports have indicated that BD may worsen during gestation due to the characteristic hypercoagulable state of pregnancy. In addition, it seems to be associated with intrauterine growth restriction secondary to infarction of placental vessels. Careful obstetric management of maternal and fetal status is mandatory in pregnancies complicated with BD. We report a successful case of a pregnancy in a patient with BD treated with low-molecular-weight heparin.<\/jats:p>","DOI":"10.1136\/bcr-2022-252306","type":"journal-article","created":{"date-parts":[[2023,12,18]],"date-time":"2023-12-18T22:30:13Z","timestamp":1702938613000},"page":"e252306","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Management of Buerger\u2019s disease during pregnancy"],"prefix":"10.1136","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9905-7167","authenticated-orcid":false,"given":"\u00c2ngela Encarna\u00e7\u00e3o","family":"Sousa Silva","sequence":"first","affiliation":[{"name":"Centro Hospitalar do M\u00e9dio Ave EPE, Vila Nova de Famalic\u00e3o, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ant\u00f3nio","family":"Braga","sequence":"additional","affiliation":[{"name":"Centro Hospitalar Universit\u00e1rio do Porto EPE Centro Materno-Infantil do Norte Dr Albino Aroso, Porto, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana","family":"Andrade","sequence":"additional","affiliation":[{"name":"Centro Hospitalar Universit\u00e1rio do Porto EPE Centro Materno-Infantil do Norte Dr Albino Aroso, Porto, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorge Sousa","family":"Braga","sequence":"additional","affiliation":[{"name":"Centro Hospitalar Universit\u00e1rio do Porto EPE Centro Materno-Infantil do Norte Dr Albino Aroso, Porto, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2023,12,18]]},"reference":[{"key":"2025082704055621000_16.12.e252306.1","unstructured":"Qaja E , Muco E , Hashmi MF . Buerger disease. Treasure Island (FL), 2023."},{"key":"2025082704055621000_16.12.e252306.2","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.ijgo.2006.03.020","article-title":"Pregnancy complicated with Buerger\u2019s disease","volume":"94","author":"Kikuchi","year":"2006","journal-title":"Intl J Gynecology & Obste"},{"key":"2025082704055621000_16.12.e252306.3","doi-asserted-by":"crossref","DOI":"10.1186\/1750-1172-1-14","article-title":"Thromboangiitis obliterans (Buerger\u2019s disease)","volume":"1","author":"Arkkila","year":"2006","journal-title":"Orphanet J Rare Dis"},{"key":"2025082704055621000_16.12.e252306.4","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1177\/0003319720920163","article-title":"Did the clinical spectrum of thromboangiitis obliterans change in the past 40 years","volume":"71","author":"Soudet","year":"2020","journal-title":"Angiology"},{"key":"2025082704055621000_16.12.e252306.5","article-title":"Thromboangiitis obliterans (Buerger\u2019s Disease)-current practices","volume":"2013","author":"Vijayakumar","year":"2013","journal-title":"Int J Inflam"},{"key":"2025082704055621000_16.12.e252306.6","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1007\/s40674-016-0047-6","article-title":"Thromboangiitis obliterans","volume":"2","author":"Akar","year":"2016","journal-title":"Curr Treat Options in Rheum"},{"key":"2025082704055621000_16.12.e252306.7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.15283\/ijsc.2010.3.1.1","article-title":"Thromoboagiitis obliterans (TAO)","volume":"3","author":"Park","year":"2010","journal-title":"Int J Stem Cells"},{"key":"2025082704055621000_16.12.e252306.8","first-page":"1","article-title":"Burger\u2019s disease: is amputation the answer","volume":"1","author":"Ariffin","year":"2019","journal-title":"J Surg Trauma Care"},{"key":"2025082704055621000_16.12.e252306.9","doi-asserted-by":"crossref","first-page":"2100","DOI":"10.1111\/jog.14087","article-title":"Case report of two pregnancies and deliveries by a woman with Buerger disease","volume":"45","author":"Ohwada","year":"2019","journal-title":"J Obstet Gynaecol Res"},{"key":"2025082704055621000_16.12.e252306.10","article-title":"An unusual case of Buerger's disease in a pregnant female","volume":"14","author":"Karena","year":"2022","journal-title":"Cureus"},{"key":"2025082704055621000_16.12.e252306.11","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1177\/000331977302400306","article-title":"Thromboangiitis obliterans in a woman. Report of a case","volume":"24","author":"Zelikovsky","year":"1973","journal-title":"Angiology"},{"key":"2025082704055621000_16.12.e252306.12","first-page":"694","article-title":"Pregnancy in a young woman with Buerger\u2019s disease. A case report","volume":"28","author":"Young","year":"1983","journal-title":"J Reprod Med"},{"key":"2025082704055621000_16.12.e252306.13","doi-asserted-by":"publisher","DOI":"10.1136\/ard.52.3.247-b"},{"key":"2025082704055621000_16.12.e252306.14","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1177\/1753495X20980251","article-title":"Thromboangiitis obliterans in pregnancy \u2013 case report and literature review","volume":"15","author":"Farquhar","year":"2022","journal-title":"Obstet Med"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2022-252306","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T11:06:14Z","timestamp":1756292774000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2022-252306"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12]]},"references-count":14,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2023,12,18]]},"published-print":{"date-parts":[[2023,12]]}},"alternative-id":["10.1136\/bcr-2022-252306"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2022-252306","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2023,12]]}}}