{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T00:05:26Z","timestamp":1756339526427,"version":"3.44.0"},"reference-count":12,"publisher":"BMJ","issue":"11","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2022,10,14]]},"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:p>Purely calvarial or intradiploic cavernous haemangiomas (PICHs) are rare benign tumours accounting for 0.2% of all bone tumours and 10% of benign skull tumours. They are generally small, slow-growing and asymptomatic lesions. Here the authors described an immunocompromised patient with concomitant giant intradiploic ossified globular cavernous angioma and multifocal neurotoxoplasmosis that underwent a combined approach to treat both lesions with an en-bloc resection of the right parietal intradiploic lesion and biopsy of the left occipital subcortical lesion.<\/jats:p>\n               <jats:p>Indeed, it is essential to exclude the presence of metastases by making a timely differential diagnosis. En-bloc surgical resection of purely intradiploic ossified cavernous angioma is the gold standard treatment and the prognosis after a complete excision is usually excellent with rarer recurrence rate.<\/jats:p>","DOI":"10.1136\/bcr-2022-252451","type":"journal-article","created":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T10:58:10Z","timestamp":1667300290000},"page":"e252451","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Concomitant giant purely intradiploic cavernous haemangioma and multifocal neurotoxoplasmosis"],"prefix":"10.1136","volume":"15","author":[{"given":"Roberta","family":"Costanzo","sequence":"first","affiliation":[{"name":"Experimental Biomedicine and Clinical Neurosciences, School of Medicine, Postgraduate Residency Program in Neurological Surgery, Neurosurgical Clinic, University of Palermo, Palermo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9465-2506","authenticated-orcid":false,"given":"Gianluca","family":"Scalia","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Garibaldi Hospital, Catania, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Domenico Gerardo","family":"Iacopino","sequence":"additional","affiliation":[{"name":"Experimental Biomedicine and Clinical Neurosciences, School of Medicine, Postgraduate Residency Program in Neurological Surgery, Neurosurgical Clinic, University of Palermo, Palermo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni","family":"Nicoletti","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Garibaldi Hospital, Catania, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2022,11,1]]},"reference":[{"key":"2025082708345856000_15.11.e252451.1","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000003069","article-title":"Primary Intraosseous cavernous hemangioma in the skull","volume":"95","author":"Yang","year":"2016","journal-title":"Medicine"},{"key":"2025082708345856000_15.11.e252451.2","doi-asserted-by":"crossref","first-page":"575","DOI":"10.3171\/2009.7.PEDS09105","article-title":"Cavernous hemangioma of the skull: surgical treatment without craniectomy","volume":"4","author":"Nasrallah","year":"2009","journal-title":"J Neurosurg Pediatr"},{"key":"2025082708345856000_15.11.e252451.3","doi-asserted-by":"crossref","first-page":"283","DOI":"10.5999\/aps.2013.40.3.283","article-title":"Primary intraosseous hemangioma in the frontal bone","volume":"40","author":"Park","year":"2013","journal-title":"Arch Plast Surg"},{"key":"2025082708345856000_15.11.e252451.4","doi-asserted-by":"crossref","first-page":"174","DOI":"10.4103\/0976-3147.83587","article-title":"Giant primary ossified cavernous hemangioma of the skull in an adult: a rare calvarial tumor","volume":"2","author":"Tyagi","year":"2011","journal-title":"J Neurosci Rural Pract"},{"key":"2025082708345856000_15.11.e252451.5","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.24036"},{"key":"2025082708345856000_15.11.e252451.6","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1055\/s-0041-1723755","article-title":"Purely intraventricular desmoplastic infantile astrocytoma","volume":"19","author":"Nicoletti","year":"2021","journal-title":"J Pediatric Neurol"},{"key":"2025082708345856000_15.11.e252451.7","doi-asserted-by":"crossref","unstructured":"Umana GE , Alberio N , Amico P . Giant cystic brain metastasis from ovarian papillary serous adenocarcinoma: case report and review of the literature. Interdiscip Neurosurg: Adv Tech Case Manag 2020.doi:10.1016\/j.inat.2020.100668","DOI":"10.1016\/j.inat.2020.100668"},{"key":"2025082708345856000_15.11.e252451.8","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.wneu.2019.10.051","article-title":"Choroid plexus carcinoma in adults: literature review and first report of a location into the third ventricle","volume":"133","author":"Crea","year":"2020","journal-title":"World Neurosurg"},{"key":"2025082708345856000_15.11.e252451.9","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.wneu.2019.07.233","article-title":"Spontaneous Subgaleal Abscess Associated with Lung Adenocarcinoma: First\u00a0Description of This Unusual Association","volume":"131","author":"Umana","year":"2019","journal-title":"World Neurosurg"},{"key":"2025082708345856000_15.11.e252451.10","doi-asserted-by":"publisher","DOI":"10.25259\/SNI_951_2020"},{"key":"2025082708345856000_15.11.e252451.11","doi-asserted-by":"crossref","DOI":"10.25259\/SNI_259_2020","article-title":"Intramedullary craniovertebral junction metastasis leading to the diagnosis of underlying renal cell carcinoma","volume":"11","author":"Ponzo","year":"2020","journal-title":"Surg Neurol Int"},{"key":"2025082708345856000_15.11.e252451.12","first-page":"207","article-title":"HIV related toxoplasmic encephalitis mimicking multiple metastasis: case report","volume":"17","author":"Ozgiray","year":"2007","journal-title":"Turk Neurosurg"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2022-252451","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T15:35:07Z","timestamp":1756308907000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2022-252451"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11]]},"references-count":12,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2022,11,1]]},"published-print":{"date-parts":[[2022,11]]}},"alternative-id":["10.1136\/bcr-2022-252451"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2022-252451","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2022,11]]}}}