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A transurethral resection of a bladder tumour was performed, and pathology revealed a high-grade adenocarcinoma consistent with a colorectal primary. A colonoscopy was unremarkable, and imaging studies showed tumour involving the bladder and prostate. Tumour markers and a CARIS genomic prevalence score also favoured a colorectal cancer primary.<\/jats:p>\n               <jats:p>The patient refused surgery and underwent chemoradiation with a combination of EBRT and brachytherapy with concurrent capecitabine. Imaging studies obtained 6 months after reirradiation revealed an enlarged left-sided mesorectal lymph node concerning for disease recurrence. The lymph node was treated with Stereotactic Body Radiation Therapy and his post-treatment imaging revealed a response to treatment with no other evidence of disease.<\/jats:p>","DOI":"10.1136\/bcr-2022-252747","type":"journal-article","created":{"date-parts":[[2023,7,18]],"date-time":"2023-07-18T22:00:18Z","timestamp":1689717618000},"page":"e252747","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Adenocarcinoma involving the urinary bladder"],"prefix":"10.1136","volume":"16","author":[{"given":"Pule","family":"Wang","sequence":"first","affiliation":[{"name":"School of Medicine, Wayne State University, Detroit, Michigan, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Joiner","sequence":"additional","affiliation":[{"name":"Oncology, Wayne State University, Detroit, Michigan, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen","family":"Dzul","sequence":"additional","affiliation":[{"name":"School of Medicine, Wayne State University, Detroit, Michigan, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven Raymond","family":"Miller","sequence":"additional","affiliation":[{"name":"Radiation Oncology, Barbara Ann Karmanos Cancer Institute, Detroit, Michigan, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2023,7,18]]},"reference":[{"key":"2025082712384657000_16.7.e252747.1","doi-asserted-by":"publisher","DOI":"10.3109\/03014460.2013.807878"},{"key":"2025082712384657000_16.7.e252747.2","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1038\/s41430-022-01251-x","article-title":"Nutritional management of cancer patients in clinical practice in Spain: patients' and Multidisciplinary health care professionals' perceptions","volume":"77","author":"S\u00e1nchez-S\u00e1nchez","year":"2023","journal-title":"Eur J Clin Nutr"},{"key":"2025082712384657000_16.7.e252747.3","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21388"},{"key":"2025082712384657000_16.7.e252747.4","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.humpath.2012.04.017","article-title":"Immunohistochemistry of colorectal carcinoma: Current practice and evolving applications","volume":"44","author":"Taliano","year":"2013","journal-title":"Hum Pathol"},{"key":"2025082712384657000_16.7.e252747.5","doi-asserted-by":"publisher","DOI":"10.1007\/s10585-012-9483-3"},{"key":"2025082712384657000_16.7.e252747.6","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.10799"},{"key":"2025082712384657000_16.7.e252747.7","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/j.eururo.2020.11.010","article-title":"A systematic review and meta-analysis of local salvage therapies after radiotherapy for prostate cancer (MASTER)","volume":"80","author":"Valle","year":"2021","journal-title":"Eur Urol"},{"key":"2025082712384657000_16.7.e252747.8","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/j.canrad.2019.07.125","article-title":"Salvage Reirradiation for local prostate cancer recurrence after radiation therapy. for who? 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