{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T05:21:59Z","timestamp":1776316919399,"version":"3.50.1"},"reference-count":16,"publisher":"BMJ","issue":"6","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2023,6,1]]},"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:p>Vertical transmission as a route of infection has been well reported in many viral infections. Scrub typhus is a zoonotic disease transmitted by ticks which has had a resurgence in recent times in several tropical countries. It affects all age groups including neonates. Reports of neonates affected with scrub typhus are few, and vertical transmission is rare. We report a case, where a newborn was symptomatic with signs of infection within the first 72 hours of life and Orientia tsutsugamushi, the causative organism was confirmed by PCR in both mother and baby.<\/jats:p>","DOI":"10.1136\/bcr-2022-253172","type":"journal-article","created":{"date-parts":[[2023,6,14]],"date-time":"2023-06-14T13:35:26Z","timestamp":1686749726000},"page":"e253172","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["Scrub typhus due to vertical transmission in a neonate: rare presentation of a common tropical infection"],"prefix":"10.1136","volume":"16","author":[{"given":"Revati","family":"Deglurkar","sequence":"first","affiliation":[{"name":"Department of Neonatology, Jawaharlal Institute of Postgraduate Medical Education and Research, JIPMER, Puducherry, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nanmaaran Periyannan","family":"Thangavel","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Jawaharlal Institute of Postgraduate Medical Education and Research, JIPMER, Puducherry, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8052-1719","authenticated-orcid":false,"given":"Ambalakkuthan","family":"Murugesan","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Jawaharlal Institute of Postgraduate Medical Education and Research, JIPMER, Puducherry, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2729-7310","authenticated-orcid":false,"given":"Nishad","family":"Plakkal","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Jawaharlal Institute of Postgraduate Medical Education and Research, JIPMER, Puducherry, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2023,6,14]]},"reference":[{"key":"2025082802313149000_16.6.e253172.1","doi-asserted-by":"publisher","DOI":"10.4103\/0974-777X.192966"},{"key":"2025082802313149000_16.6.e253172.2","doi-asserted-by":"publisher","DOI":"10.1258\/td.2010.100132"},{"key":"2025082802313149000_16.6.e253172.3","doi-asserted-by":"publisher","DOI":"10.1177\/1753495X16638952"},{"key":"2025082802313149000_16.6.e253172.4","first-page":"1","article-title":"A case series of scrub typhus in Obstetrics","volume":"8","author":"Poomalar","year":"2014","journal-title":"J Clin Diagn Res"},{"issue":"5 Pt 1","key":"2025082802313149000_16.6.e253172.5","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1542\/peds.89.5.965","article-title":"Neonatal scrub typhus: a case report","volume":"89","author":"Wang","year":"1992","journal-title":"Pediatrics"},{"key":"2025082802313149000_16.6.e253172.6","doi-asserted-by":"publisher","DOI":"10.1111\/j.1447-0756.1997.tb00809.x"},{"key":"2025082802313149000_16.6.e253172.7","doi-asserted-by":"crossref","first-page":"343","DOI":"10.4103\/0255-0857.118874","article-title":"First case series of emerging Rickettsial neonatal sepsis identified by polymerase chain reaction-based Deoxyribonucleic acid sequencing","volume":"31","author":"Aarthi","year":"2013","journal-title":"Indian J Med Microbiol"},{"key":"2025082802313149000_16.6.e253172.8","first-page":"2","article-title":"Neonatal scrub typhus: case report","volume":"1","author":"Gothwal","year":"2016","journal-title":"Pediatr Emerg Care Med Open Access"},{"key":"2025082802313149000_16.6.e253172.9","unstructured":"Perumal SK . Primary neonatal scrub typhus-a case report. University Journal of Medicine and Medical Specialities, 2017."},{"key":"2025082802313149000_16.6.e253172.10","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/s12664-017-0761-5","article-title":"Scrub typhus causing neonatal hepatitis with acute liver failure-A case series","volume":"36","author":"Vajpayee","year":"2017","journal-title":"Indian J Gastroenterol"},{"key":"2025082802313149000_16.6.e253172.11","first-page":"SD05","article-title":"Scrub typhus in a new born","volume":"11","author":"Jajoo","year":"2017","journal-title":"J Clin Diagn Res"},{"key":"2025082802313149000_16.6.e253172.12","first-page":"836","article-title":"Neonatal scrub typhus: case report","volume":"7","author":"Paramanantham","year":"2018","journal-title":"World J Pharm Res"},{"key":"2025082802313149000_16.6.e253172.13","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1007\/s13312-020-1864-0","article-title":"Clinical profile of scrub typhus in newborns","volume":"57","author":"Samad","year":"2020","journal-title":"Indian Pediatr"},{"key":"2025082802313149000_16.6.e253172.14","doi-asserted-by":"crossref","first-page":"173","DOI":"10.4103\/ipcares.ipcares_138_21","article-title":"Neonatal scrub typhus\u2013A sepsis Mimic","volume":"1","author":"Reddy","year":"2021","journal-title":"Indian Pediatrics Case Reports"},{"key":"2025082802313149000_16.6.e253172.15","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1177\/09732179221100609","article-title":"Neonatal scrub typhus\u2014A case report","volume":"36","author":"Mehta","year":"2022","journal-title":"Journal of Neonatology"},{"key":"2025082802313149000_16.6.e253172.16","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1111\/tmi.13322","article-title":"Antibody response following scrub typhus infection: clinical cohort study","volume":"24","author":"Schmidt","year":"2019","journal-title":"Trop Med Int Health"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2022-253172","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T09:31:46Z","timestamp":1756373506000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2022-253172"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6]]},"references-count":16,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2023,6,14]]},"published-print":{"date-parts":[[2023,6]]}},"alternative-id":["10.1136\/bcr-2022-253172"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2022-253172","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,6]]}}}