{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T19:15:02Z","timestamp":1790363702890,"version":"4.1.0"},"reference-count":8,"publisher":"BMJ","issue":"8","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2023,7,31]]},"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:p>The anterior cruciate ligament (ACL) is the most frequently injured knee ligament, typically in non-contact athletic injuries in young adults. Mucoid degeneration of the ACL (ACL-MD) is an uncommon ACL pathology in which glycosaminoglycans deposition within the collagenous bundles leads to hypertrophy, loss of full knee flexion and knee pain without instability. ACL-MD usually presents in individuals over 40 years with sudden-onset knee pain after minimal trauma or as an incidental MRI finding. ACL-MD is rarely described in young adults. We present a case of ACL-MD in a previously healthy adult in his early 20s who presented with 3-month recalcitrant dull left knee pain and limited range of motion after \u2018stepping funny\u2019 with slight twisting. This case highlights the need to critically reflect on the anatomical structures when presented with musculoskeletal pathologies and to consider the unique presentation of musculoskeletal disease in atypical age groups.<\/jats:p>","DOI":"10.1136\/bcr-2022-253307","type":"journal-article","created":{"date-parts":[[2023,8,14]],"date-time":"2023-08-14T11:35:33Z","timestamp":1692012933000},"page":"e253307","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Mucoid degeneration of the anterior cruciate ligament corrected with autograft reconstruction"],"prefix":"10.1136","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0702-7209","authenticated-orcid":false,"given":"Ali Zagham","family":"Nasir","sequence":"first","affiliation":[{"name":"Internal Medicine Residency, Trinity Health Grand Rapids Hospital, Grand Rapids, Michigan, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy","family":"Henne","sequence":"additional","affiliation":[{"name":"Orthopaedics, Trinity Health Grand Rapids Hospital, Grand Rapids, Michigan, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nasir","family":"Khan","sequence":"additional","affiliation":[{"name":"Internal Medicine, Trinity Health Grand Rapids Hospital, Grand Rapids, Michigan, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2023,8,14]]},"reference":[{"key":"2025082707104717000_16.8.e253307.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.csm.2016.08.001"},{"key":"2025082707104717000_16.8.e253307.2","doi-asserted-by":"crossref","unstructured":"Vaishya R , Esin Issa A , Agarwal AK , et al . Anterior cruciate ligament ganglion cyst and Mucoid degeneration: a review. Cureus 2017;9. doi:10.7759\/cureus.1682","DOI":"10.7759\/cureus.1682"},{"key":"2025082707104717000_16.8.e253307.3","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-011-1433-0"},{"key":"2025082707104717000_16.8.e253307.4","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1007\/s00776-009-1432-x","article-title":"Mucoid degeneration of the anterior cruciate ligament associated with subclinical instability in young patients","volume":"15","author":"Niki","year":"2010","journal-title":"J Orthop Sci"},{"key":"2025082707104717000_16.8.e253307.5","first-page":"95","article-title":"Early reconstruction should be considered in younger patients with symptomatic mucoid degeneration of the anterior cruciate ligament","volume":"2","author":"Kusano","year":"2015","journal-title":"Asia Pac J Sports Med Arthrosc Rehabil Technol"},{"key":"2025082707104717000_16.8.e253307.6","doi-asserted-by":"crossref","first-page":"2983","DOI":"10.1007\/s00167-023-07311-4","article-title":"The anterior cruciate ligament injury severity scale (ACLISS) is an effective tool to document and categorize the magnitude of associated tissue damage in knees after primary ACL injury and reconstruction","volume":"31","author":"Seil","year":"2023","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"key":"2025082707104717000_16.8.e253307.7","doi-asserted-by":"publisher","DOI":"10.1007\/s11845-009-0311-y"},{"key":"2025082707104717000_16.8.e253307.8","doi-asserted-by":"crossref","first-page":"197","DOI":"10.4103\/0019-5413.128765","article-title":"Mucoid degeneration of the anterior cruciate ligament: management and outcome","volume":"48","author":"Pandey","year":"2014","journal-title":"IJOO"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2022-253307","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T14:10:55Z","timestamp":1756303855000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2022-253307"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8]]},"references-count":8,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2023,8,14]]},"published-print":{"date-parts":[[2023,8]]}},"alternative-id":["10.1136\/bcr-2022-253307"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2022-253307","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,8]]}}}