{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T01:05:58Z","timestamp":1792803958703,"version":"4.5.0"},"reference-count":5,"publisher":"BMJ","issue":"1","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2022,12,29]]},"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:p>Diffuse large B-cell lymphoma (DLBCL) is the most common lymphoid malignancy in adults. It manifests a variable presentation, depending on the tissue in which it arises. Rarely, it can present as dysphagia to solid and liquid foods in primary oesophageal lymphoma with or without B symptoms. We present a case of a 66-year-old man who presented with 3 months of progressive dysphagia with only a mild associated weight loss. This was later found to be caused by DLBCL of the mediastinum causing external compression of the patient\u2019s distal oesophagus and gastric cardia. He was treated with one cycle of standard-of-care chemotherapy and subsequently discharged with outpatient follow-up. We emphasise the importance of ruling out life-threatening conditions such as lymphoma in patients who present with dysphagia, as well as the high variability in presentation of DLBCL.<\/jats:p>","DOI":"10.1136\/bcr-2022-253357","type":"journal-article","created":{"date-parts":[[2023,1,12]],"date-time":"2023-01-12T09:46:54Z","timestamp":1673516814000},"page":"e253357","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Chronic dysphagia as a presenting complaint for primary mediastinal diffuse large B-cell lymphoma"],"prefix":"10.1136","volume":"16","author":[{"given":"Logan","family":"Eslinger","sequence":"first","affiliation":[{"name":"University of Kentucky College of Medicine, Lexington, Kentucky, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taimoor","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, University of Kentucky Medical Center, Lexington, Kentucky, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samra Haroon","family":"Lodhi","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, University of Kentucky Medical Center, Lexington, Kentucky, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1337-7689","authenticated-orcid":false,"given":"Taha","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, University of Kentucky Medical Center, Lexington, Kentucky, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2023,1,12]]},"reference":[{"key":"2025082804451086000_16.1.e253357.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.critrevonc.2012.12.009"},{"key":"2025082804451086000_16.1.e253357.2","doi-asserted-by":"crossref","DOI":"10.4081\/hr.2018.7070","article-title":"Extranodal diffuse large B-cell lymphomas: a retrospective case series and review of the literature","volume":"10","author":"Boussios","year":"2018","journal-title":"Hematol Rep"},{"key":"2025082804451086000_16.1.e253357.3","first-page":"232470961882088","article-title":"Primary esophageal diffuse large B-cell lymphoma: a comparative review of 15 cases","volume":"6","author":"Inayat","year":"2018","journal-title":"J Investig Med High Impact Case Rep"},{"key":"2025082804451086000_16.1.e253357.4","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1044\/2020_AJSLP-19-00189","article-title":"Best practices in modified barium swallow studies","volume":"29","author":"Martin-Harris","year":"2020","journal-title":"Am J Speech Lang Pathol"},{"key":"2025082804451086000_16.1.e253357.5","doi-asserted-by":"crossref","first-page":"e865","DOI":"10.1016\/j.clml.2021.06.012","article-title":"Primary mediastinal B-cell lymphoma: a 2021 update on genetics, diagnosis, and novel therapeutics","volume":"21","author":"Ahmed","year":"2021","journal-title":"Clin Lymphoma Myeloma Leuk"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2022-253357","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T11:45:16Z","timestamp":1756381516000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2022-253357"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":5,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2023,1,12]]},"published-print":{"date-parts":[[2023,1]]}},"alternative-id":["10.1136\/bcr-2022-253357"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2022-253357","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1]]}}}