{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T17:40:03Z","timestamp":1756316403697,"version":"3.44.0"},"reference-count":18,"publisher":"BMJ","issue":"9","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2023,9,10]]},"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:p>Seronegative villous atrophy (SNVA) is a diagnostic challenge for gastroenterologists, which is defined by villous atrophy and negative coeliac serology. Non-coeliac forms of SNVA, such as autoimmune enteropathy, can be life-threatening leading to intractable diarrhoea and severe malabsorption that require systemic immunosuppression. When all known causes have been excluded, it is termed idiopathic villous atrophy (IVA). We present a case of non-coeliac SNVA complicated by Kaposi sarcoma (KS). A previously well HIV-negative man in his 30s presented with a 4-month history of watery diarrhoea and 25\u2009kg weight loss. After prolonged investigation, he was diagnosed with non-coeliac SNVA without an identified aetiology that would be consistent with IVA. Clinical recovery was achieved with parenteral nutrition for type II intestinal failure and immunosuppression using high-dose corticosteroids. On subsequent gastroscopy, he was diagnosed with localised intestinal KS prompting cessation of all immunosuppression but remained in clinical remission.<\/jats:p>","DOI":"10.1136\/bcr-2022-254073","type":"journal-article","created":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T13:06:38Z","timestamp":1695733598000},"page":"e254073","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Localised intestinal Kaposi sarcoma in a patient with non-coeliac seronegative villous atrophy"],"prefix":"10.1136","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2058-3162","authenticated-orcid":false,"given":"Benjamin","family":"Norton","sequence":"first","affiliation":[{"name":"Gastroenterology, Barnet and Chase Farm Hospitals NHS Trust, London, UK"},{"name":"Gastroenterology, University College London Hospitals NHS Foundation Trust, London, UK"},{"name":"Centre for Obesity Research, Rayne Institute, Department of 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