{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T07:40:04Z","timestamp":1756366804730,"version":"3.44.0"},"reference-count":15,"publisher":"BMJ","issue":"3","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2023,2,28]]},"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:p>Lymphoma of a dural genesis is a distinct variant of primary central nervous system lymphoma and is rare. It putatively has a more benign clinical course. Cranial primary dural lymphoma is more often marginal zone B-cell lymphoma, whereas spinal primary dural lymphoma is most commonly diffuse large B-cell lymphoma.<\/jats:p>\n               <jats:p>We report a male patient who presented with subacute progressive radiculopathy due to a compressive infiltrative lumbosacral spinal lesion. This was determined to be primary dural diffuse large B-cell lymphoma. The radiology, therapeutic considerations and differentiating biological characteristics of primary dural lymphoma, differ from other primary central nervous system lymphomas.<\/jats:p>\n               <jats:p>Primary dural lymphoma is under-represented in the medical literature. It has unique clinical characteristics. The optimal treatment algorithm remains undefined, but there is some evidence suggesting a benefit of surgical cytoreductive therapy in the first instance, and low-dose radiotherapy may be an effective adjuvant therapy in addition to chemotherapeutic and immunotherapeutic agents.<\/jats:p>","DOI":"10.1136\/bcr-2022-254093","type":"journal-article","created":{"date-parts":[[2023,3,27]],"date-time":"2023-03-27T01:05:44Z","timestamp":1679879144000},"page":"e254093","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Lumbar radiculopathy secondary to primary spinal dural diffuse large B-cell lymphoma"],"prefix":"10.1136","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9237-7395","authenticated-orcid":false,"given":"Christopher Alan","family":"Brooks","sequence":"first","affiliation":[{"name":"Neurosurgery, Waikato Hospital, Hamilton, Waikato, New 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