{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,17]],"date-time":"2026-05-17T15:56:00Z","timestamp":1779033360340,"version":"3.51.4"},"reference-count":8,"publisher":"BMJ","issue":"9","license":[{"start":{"date-parts":[[2023,9,18]],"date-time":"2023-09-18T00:00:00Z","timestamp":1694995200000},"content-version":"unspecified","delay-in-days":17,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2023,7,23]]},"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:p>A woman in her 40s was admitted to hospital with weight loss, asthenia, persistent abdominal pain and post-prandial nausea and vomiting. Other comorbidities were anxiety-depressive disorder, gastro-oesophageal reflux disease and fibrocystic mastopathy. On admission her body mass index (BMI) was 15.57\u2009kg\/m<jats:sup>2<\/jats:sup> with a reported weight loss of 6\u2009kg during the last 3\u2009months. The patient underwent a double contrast abdominal CT scan, which showed that the third portion of the duodenum appeared to be compressed between the superior mesenteric artery and the abdominal aorta. After a multidisciplinary evaluation, a conservative approach and nutritional supplementation was decided upon and administered. At the 1-year follow-up the symptoms had greatly improved; the epigastric pain, although persistent, was reduced, also due to the weight gain to 50\u2009kg (BMI 19.5\u2009kg\/m<jats:sup>2<\/jats:sup>). Wilkie\u2019s syndrome, in its acquired form, predominantly affects young women after rapid weight loss. In the diagnostic work-up, case history, physical examination and radiological findings play a key role.<\/jats:p>","DOI":"10.1136\/bcr-2022-254157","type":"journal-article","created":{"date-parts":[[2023,9,18]],"date-time":"2023-09-18T22:50:37Z","timestamp":1695077437000},"page":"e254157","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":7,"title":["Aorto\u2013mesenteric compass syndrome (Wilkie\u2019s syndrome) in the differential diagnosis of chronic abdominal pain"],"prefix":"10.1136","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0838-4478","authenticated-orcid":false,"given":"Angelo","family":"Forte","sequence":"first","affiliation":[{"name":"Department of Clinical Medicine and Surgery, University of Naples \u201cFederico II\u201d, Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lidia","family":"Santarpia","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine and Surgery, University of Naples \u201cFederico II\u201d, Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Piero","family":"Venetucci","sequence":"additional","affiliation":[{"name":"Advanced Biomedical Sciences Department, University Federico II of Naples, Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4660-821X","authenticated-orcid":false,"given":"Antonio","family":"Barbato","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine and Surgery, University of Naples \u201cFederico II\u201d, Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2023,9,18]]},"reference":[{"key":"2025082710112078000_16.9.e254157.1","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1159\/000506620","article-title":"Superior mesenteric artery syndrome improved by enteral nutritional therapy","volume":"76","author":"Wan","year":"2020","journal-title":"Ann Nutr Metab"},{"key":"2025082710112078000_16.9.e254157.2","first-page":"628705","article-title":"Superior mesenteric artery syndrome: clinical and radiological considerations","volume":"2015","author":"Rabie","year":"2015","journal-title":"Surg Res Pract"},{"key":"2025082710112078000_16.9.e254157.3","article-title":"Wilkie\u2019s syndrome as a rare cause of duodenal obstruction: perspicacity is in the radiological details","volume":"12","author":"Al Faqeeh","year":"2020","journal-title":"Cureus"},{"key":"2025082710112078000_16.9.e254157.4","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1308\/rcsann.2017.0063","article-title":"Superior mesenteric artery syndrome: a single centre experience of laparoscopic duodenojejunostomy as the operation of choice","volume":"99","author":"Kirby","year":"2017","journal-title":"Ann R Coll Surg Engl"},{"key":"2025082710112078000_16.9.e254157.5","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1007\/s40477-017-0257-2","article-title":"Wilkie\u2019s syndrome","volume":"20","author":"Farina","year":"2017","journal-title":"J Ultrasound"},{"key":"2025082710112078000_16.9.e254157.6","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2012.04.032"},{"key":"2025082710112078000_16.9.e254157.7","first-page":"546","article-title":"Superior mesenteric artery syndrome (Wilkie syndrome): case report","volume":"106","author":"Fiorini","year":"2008","journal-title":"Arch Argent Pediatr"},{"key":"2025082710112078000_16.9.e254157.8","first-page":"R01","article-title":"A case series on superior mesenteric artery syndrome surgical management, single institution experience","volume":"11","author":"Valiathan","year":"2017","journal-title":"J Clin Diagn Res"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2022-254157","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T17:11:29Z","timestamp":1756314689000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2022-254157"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9]]},"references-count":8,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2023,9,18]]},"published-print":{"date-parts":[[2023,9]]}},"alternative-id":["10.1136\/bcr-2022-254157"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2022-254157","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,9]]}}}