{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T10:10:25Z","timestamp":1756289425591,"version":"3.44.0"},"reference-count":10,"publisher":"BMJ","issue":"1","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2023,10,11]]},"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:p>Crohn\u2019s disease patients often need regular home parenteral nutrition (HPN) for intestinal failure due to multiple intestinal resections. Trace elements are necessary for long-term HPN but the requirement volume of iron is undetermined. We describe three patients with Crohn\u2019s disease with short bowel syndrome (SBS) who had iron overload as a result of long-term HPN including iron. Serum ferritin level was significantly decreased through depleting intravenous iron administration in all cases. One patient needed regular insulin injection and phlebotomy for diabetes mellitus due to hemochromatosis, and intravenous iron administration had a significant impact on the patient\u2019s health. Long-term routine intravenous iron administration should be cautious in SBS patients to avoid the overload.<\/jats:p>","DOI":"10.1136\/bcr-2023-254612","type":"journal-article","created":{"date-parts":[[2024,1,25]],"date-time":"2024-01-25T12:21:02Z","timestamp":1706185262000},"page":"e254612","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Iron overload in patients with Crohn\u2019s disease with short bowel syndrome who received long-term parenteral nutrition with trace elements"],"prefix":"10.1136","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0314-9196","authenticated-orcid":false,"given":"Yosuke","family":"Shimodaira","sequence":"first","affiliation":[{"name":"School of Medicine, Akita University Graduate School of Medicine, Akita City, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sho","family":"Fukuda","sequence":"additional","affiliation":[{"name":"School of Medicine, Akita University Graduate School of Medicine, Akita City, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"So","family":"Takahashi","sequence":"additional","affiliation":[{"name":"School of Medicine, Akita University Graduate School of Medicine, Akita City, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katsunori","family":"Iijima","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Neurology, Akita University Graduate School of Medicine, Akita, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2024,1,25]]},"reference":[{"doi-asserted-by":"publisher","key":"2025082702403351000_17.1.e254612.1","DOI":"10.1016\/S0140-6736(12)60026-9"},{"doi-asserted-by":"publisher","key":"2025082702403351000_17.1.e254612.2","DOI":"10.1038\/ajg.2014.297"},{"doi-asserted-by":"publisher","key":"2025082702403351000_17.1.e254612.3","DOI":"10.1007\/s00535-013-0797-y"},{"key":"2025082702403351000_17.1.e254612.4","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1016\/j.clnu.2020.03.005","article-title":"ESPEN guideline on home parenteral nutrition","volume":"39","author":"Pironi","year":"2020","journal-title":"Clin Nutr"},{"doi-asserted-by":"publisher","key":"2025082702403351000_17.1.e254612.5","DOI":"10.1136\/gut.2010.223255"},{"key":"2025082702403351000_17.1.e254612.6","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1111\/j.1365-2036.2012.05051.x","article-title":"Review article: the iron overload syndromes","volume":"35","author":"Siddique","year":"2012","journal-title":"Aliment Pharmacol Ther"},{"doi-asserted-by":"publisher","key":"2025082702403351000_17.1.e254612.7","DOI":"10.1016\/j.clnu.2016.01.020"},{"doi-asserted-by":"publisher","key":"2025082702403351000_17.1.e254612.8","DOI":"10.1177\/01486071040280S601"},{"doi-asserted-by":"publisher","key":"2025082702403351000_17.1.e254612.9","DOI":"10.1177\/0884533612463440"},{"doi-asserted-by":"publisher","key":"2025082702403351000_17.1.e254612.10","DOI":"10.1177\/0148607115587329"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2023-254612","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T09:40:44Z","timestamp":1756287644000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2023-254612"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":10,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,1,25]]},"published-print":{"date-parts":[[2024,1]]}},"alternative-id":["10.1136\/bcr-2023-254612"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2023-254612","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2024,1]]}}}