{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T00:05:28Z","timestamp":1756339528077,"version":"3.44.0"},"reference-count":17,"publisher":"BMJ","issue":"6","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2023,6,11]]},"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:p>A man in his early 20s with heart failure with reduced ejection fraction secondary to non-compaction cardiomyopathy (Titin (TTN) gene mutation positive) was transitioned from left ventricular assist device (LVAD) mechanical support to heart transplantation. Transplantation was successful; however, LVAD explantation resulted in innumerable complications secondary to penetration of the driveline into the peritoneal cavity. He developed an enterocutaneous fistula which led to concurrent malnutrition, poor wound healing, systemic infection, and allograft rejection in a patient less than 1\u2009month after heart transplantation on immunosuppression.<\/jats:p>","DOI":"10.1136\/bcr-2023-254696","type":"journal-article","created":{"date-parts":[[2023,6,23]],"date-time":"2023-06-23T04:15:22Z","timestamp":1687493722000},"page":"e254696","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Enterocutaneous fistula formation after cardiac transplantation due to injury from LVAD driveline migration"],"prefix":"10.1136","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0590-870X","authenticated-orcid":false,"given":"Derek W","family":"Tan","sequence":"first","affiliation":[{"name":"Department of Anesthesiology, Jackson Memorial Hospital, Miami, Florida, USA"},{"name":"Department of Anesthesiology, University of Miami Hospital and Clinics, Miami, Florida, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1724-4231","authenticated-orcid":false,"given":"Crystal Lihong","family":"Yan","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Jackson Memorial Hospital, Miami, Florida, USA"},{"name":"Department of Internal Medicine, University of Miami Hospital and Clinics, Miami, Florida, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel Dante","family":"Yeh","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of Colorado Denver, Denver, Colorado, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nina","family":"Thakkar-Rivera","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Jackson Memorial Hospital, Miami, Florida, USA"},{"name":"Department of Cardiology, University of Miami Hospital and Clinics, Miami, Florida, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2023,6,22]]},"reference":[{"key":"2025082708462822000_16.6.e254696.1","doi-asserted-by":"publisher","DOI":"10.31486\/toj.19.0022"},{"key":"2025082708462822000_16.6.e254696.2","unstructured":"US Department of Health and Human Services - HRSA\/SRTR . OPTN\/SRTR 2020 annual data report. Heart; 2020. Available: https:\/\/srtr.transplant.hrsa.gov\/annualreports\/2020\/Heart.aspx"},{"key":"2025082708462822000_16.6.e254696.3","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1186\/s13019-018-0738-1","article-title":"Bowel obstruction due to retained intraperitoneal left ventricular assist device (LVAD) Driveline","volume":"13","author":"Miklin","year":"2018","journal-title":"J Cardiothorac Surg"},{"key":"2025082708462822000_16.6.e254696.4","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1186\/s13019-020-01240-w","article-title":"Colonic Perforation due to inadvertent intraperitoneal LVAD Driveline placement","volume":"15","author":"Shnaydman","year":"2020","journal-title":"J Cardiothorac Surg"},{"key":"2025082708462822000_16.6.e254696.5","first-page":"226","article-title":"Driveline erosion of the colon as a late complication of LVAD implantation","volume":"27","author":"Yan","year":"2023","journal-title":"J Cardiol Cases"},{"key":"2025082708462822000_16.6.e254696.6","article-title":"Enterocutaneous Fistula: a simplified clinical approach","volume":"12","author":"Tuma","year":"2020","journal-title":"Cureus"},{"key":"2025082708462822000_16.6.e254696.7","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1055\/s-0036-1580732","article-title":"Enterocutaneous Fistula: proven strategies and updates","volume":"29","author":"Gribovskaja-Rupp","year":"2016","journal-title":"Clin Colon Rectal Surg"},{"key":"2025082708462822000_16.6.e254696.8","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0259300","article-title":"The prevalence of malnutrition and its effects on the all-cause mortality among patients with heart failure: A systematic review and meta-analysis","volume":"16","author":"Lv","year":"2021","journal-title":"PLOS ONE"},{"key":"2025082708462822000_16.6.e254696.9","doi-asserted-by":"crossref","DOI":"10.3390\/nu12123868","article-title":"Survival and nutritional status of male and female heart transplant patients based on the nutritional risk index","volume":"12","author":"Almutawa","year":"2020","journal-title":"Nutrients"},{"key":"2025082708462822000_16.6.e254696.10","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1016\/j.numecd.2022.03.009","article-title":"Prediction of all-cause mortality with malnutrition assessed by nutritional screening and assessment tools in patients with heart failure: a systematic review","volume":"32","author":"Hu","year":"2022","journal-title":"Nutr Metab Cardiovasc Dis"},{"key":"2025082708462822000_16.6.e254696.11","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccc.2016.12.001"},{"key":"2025082708462822000_16.6.e254696.12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2014.04.083"},{"key":"2025082708462822000_16.6.e254696.13","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1097\/TA.0b013e3182aafe6b","article-title":"Persistent inflammation-immunosuppression catabolism syndrome, a common manifestation of patients with Enterocutaneous Fistula in intensive care unit","volume":"76","author":"Hu","year":"2014","journal-title":"J Trauma Acute Care Surg"},{"key":"2025082708462822000_16.6.e254696.14","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1111\/j.1742-481X.2012.00950.x","article-title":"Effects of immunosuppressive therapy on wound healing","volume":"10","author":"Bootun","year":"2013","journal-title":"Int Wound J"},{"key":"2025082708462822000_16.6.e254696.15","doi-asserted-by":"publisher","DOI":"10.1590\/abd1806-"},{"key":"2025082708462822000_16.6.e254696.16","doi-asserted-by":"crossref","unstructured":"Hashim HT , Ahmed N , Faggian G , et al . Heart transplantation. StatPearls, 2022. doi:10.1007\/978-3-031-17311-0","DOI":"10.1007\/978-3-031-17311-0"},{"key":"2025082708462822000_16.6.e254696.17","unstructured":"Ludhwani D , Abraham J . Heart Transplantation Rejection. StatPearls, 2022. Available: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK537057"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2023-254696","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T15:46:37Z","timestamp":1756309597000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2023-254696"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6]]},"references-count":17,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2023,6,22]]},"published-print":{"date-parts":[[2023,6]]}},"alternative-id":["10.1136\/bcr-2023-254696"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2023-254696","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2023,6]]}}}