{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T00:06:06Z","timestamp":1756339566635,"version":"3.44.0"},"reference-count":18,"publisher":"BMJ","issue":"11","funder":[{"DOI":"10.13039\/501100005809","name":"Hyderabad Eye Research Foundation","doi-asserted-by":"publisher","award":["LEC-BHR-C-15-23-155"],"award-info":[{"award-number":["LEC-BHR-C-15-23-155"]}],"id":[{"id":"10.13039\/501100005809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2023,10,19]]},"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:p>A woman in her late 50s presented with on-and-off redness and diminution of vision in her left eye for 6 months. Her best corrected visual acuity was 20\/40 in the right eye and hand motion in the left eye. Anterior segment examination revealed a greyish-white lesion extending from 3 to 6 o\u2019clock hours posterior to the iris and protruding into the anterior chamber. Left eye B-scan ultrasonography showed a multifocal choroidal lesion, a smaller one involving the posterior pole, and a larger lesion involving the complete nasal quadrant and anteriorly extending to the ciliary body and iris. Fine-needle aspiration biopsy performed from the anterior lesion showed a possible neoplastic aetiology of melanocytic origin of the cells. Finally, the patient underwent left eye enucleation with a ball implant. Histopathological examination of the enucleated eye confirmed the final diagnosis of multifocal choroidal melanoma involving the adjacent ciliary body and iris.<\/jats:p>","DOI":"10.1136\/bcr-2023-255009","type":"journal-article","created":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T13:09:07Z","timestamp":1698844147000},"page":"e255009","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Multifocal choroidal melanoma: a clinicohistopathological correlation"],"prefix":"10.1136","volume":"16","author":[{"given":"Manasi","family":"Ketkar","sequence":"first","affiliation":[{"name":"Anant Bajaj Retina Institute, LV Prasad Eye Institute, Hyderabad, Telangana, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saumya","family":"Jakati","sequence":"additional","affiliation":[{"name":"Department of Ophthalmic Pathology Laboratory, LV Prasad Eye Institute, Hyderabad, Telangana, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vishal","family":"Raval","sequence":"additional","affiliation":[{"name":"Anant Bajaj Retina Institute,The Operation Eyesight Universal Institute for Eye Cancer, LV Prasad Eye Institute, Hyderabad, Telangana, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2023,11,1]]},"reference":[{"key":"2025082710415746000_16.11.e255009.1","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1097\/ICU.0000000000000041","article-title":"Choroidal melanoma: clinical features, classification, and top 10 pseudomelanomas","volume":"25","author":"Shields","year":"2014","journal-title":"Curr Opin Ophthalmol"},{"key":"2025082710415746000_16.11.e255009.2","doi-asserted-by":"crossref","first-page":"NP102","DOI":"10.1177\/1120672120936182","article-title":"Multimodal imaging of amelanotic choroidal melanoma","volume":"31","author":"Pierro","year":"2021","journal-title":"Eur J Ophthalmol"},{"key":"2025082710415746000_16.11.e255009.3","doi-asserted-by":"crossref","first-page":"2089","DOI":"10.4103\/ijo.IJO_1773_18","article-title":"Multifocal choroidal melanoma in oculodermal melanocytosis in an Asian Indian","volume":"67","author":"Rao","year":"2019","journal-title":"Indian J Ophthalmol"},{"key":"2025082710415746000_16.11.e255009.4","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.preteyeres.2018.09.003","article-title":"New concepts in the diagnosis and management of choroidal metastases","volume":"68","author":"Mathis","year":"2019","journal-title":"Prog Retin Eye Res"},{"key":"2025082710415746000_16.11.e255009.5","doi-asserted-by":"crossref","first-page":"93","DOI":"10.4103\/0974-620X.137171","article-title":"Medulloepithelioma: a Triad of clinical features","volume":"7","author":"Peshtani","year":"2014","journal-title":"Oman J Ophthalmol"},{"key":"2025082710415746000_16.11.e255009.6","first-page":"41","article-title":"Clinical and histopathological characteristics of Uveal melanoma in Asian Indians. 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