{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T16:18:13Z","timestamp":1764260293390,"version":"3.44.0"},"reference-count":19,"publisher":"BMJ","issue":"4","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2023,3,26]]},"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>Gastrointestinal stromal tumours (GISTs) are malignant mesenchymal tumours that originate from the interstitial pacemaker cells of Cajal. They are particularly rare, comprising only 5% of all GISTs, and often present at an advanced stage. Treatment for these tumours is still a topic of debate due to their low incidence and insidious location. A woman in her mid-70s presented with rectal bleeding and anal discomfort. A 4.5\u00d74\u2009cm anal GIST was diagnosed. A local excision was performed and the patient was further treated with tyrosine kinase inhibitors. At a 6-month follow-up, the MRI showed that she was disease free. Anorectal GISTs are unusual and tend to be aggressive. Surgical resection is the first-line treatment for primary, localised GISTs. However, the appropriate surgical technique for these tumours is still a topic of debate. Further studies are needed to fully understand the oncologic behaviour of these rare neoplasms.<\/jats:p>","DOI":"10.1136\/bcr-2023-255040","type":"journal-article","created":{"date-parts":[[2023,4,7]],"date-time":"2023-04-07T10:30:20Z","timestamp":1680863420000},"page":"e255040","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Anal canal gastrointestinal stromal tumour (GIST)"],"prefix":"10.1136","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3191-4369","authenticated-orcid":false,"given":"Francesco","family":"Brucchi","sequence":"first","affiliation":[{"name":"General Surgery Residency Program, University of Milan, Milan, Milano, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"Lauricella","sequence":"additional","affiliation":[{"name":"Department of Surgery, Ospedale Citta' di Sesto San Giovanni, Sesto San Giovanni, Lombardia, 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