{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T10:01:32Z","timestamp":1771236092196,"version":"3.50.1"},"reference-count":14,"publisher":"BMJ","issue":"9","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2023,8,26]]},"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:p>Cherubism, also known as familial fibrodysplasia of the jaw, is an autosomal dominant disorder with variable penetrance. The disease process is characterised by painless and progressive bilateral enlargement of the maxillofacial skeleton. We present an adolescent female with a family history of cherubism who presented to the Oral and Maxillofacial Surgery clinic with progressive bilateral swelling of the mandible. The diagnosis of cherubism was established through a thorough history which was confirmed with an incisional biopsy. The progressive swelling negatively affected her appearance and psychosocial well-being. The patient opted for surgical intervention after a course of conservative management. Although there is often resolution of these lesions into adulthood, surgical intervention may be considered when managing this condition in adolescence. Integration with virtual surgical planning can aid in obtaining desired postoperative outcomes.<\/jats:p>","DOI":"10.1136\/bcr-2023-255059","type":"journal-article","created":{"date-parts":[[2023,9,5]],"date-time":"2023-09-05T11:40:11Z","timestamp":1693914011000},"page":"e255059","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Surgical management of mandibular cherubism in an adolescent: integration of virtual surgical planning"],"prefix":"10.1136","volume":"16","author":[{"given":"Emily","family":"Ladnier","sequence":"first","affiliation":[{"name":"Oral and Maxillofacial Surgery, Geisinger Health System, Danville, Pennsylvania, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atmiya","family":"Sheth","sequence":"additional","affiliation":[{"name":"Oral and Maxillofacial Surgery, Geisinger Health System, Danville, Pennsylvania, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9569-5428","authenticated-orcid":false,"given":"Raymond Patrick","family":"Shupak","sequence":"additional","affiliation":[{"name":"Oral and Maxillofacial Surgery, Geisinger Health System, Danville, Pennsylvania, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2023,9,5]]},"reference":[{"key":"2025082709462360000_16.9.e255059.1","doi-asserted-by":"crossref","unstructured":"Miloro M , Ghali GE , Larsen PE , et al . 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In: Adam MP , Everman DB , Mirzaa GM , eds. GeneReviews\u00ae. 2007."},{"key":"2025082709462360000_16.9.e255059.7","first-page":"4656","article-title":"Case report Cherubism Misdiagnosed as giant cell tumor: a case report and review of literature","volume":"8","author":"Jiao","year":"2015","journal-title":"Int J Clin Exp Med"},{"key":"2025082709462360000_16.9.e255059.8","first-page":"304","article-title":"Giant-cell tumor of the mandible","volume":"32","author":"Giri","year":"1946","journal-title":"Am J Orthod Oral Surg"},{"key":"2025082709462360000_16.9.e255059.9","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1016\/j.joms.2019.02.021","article-title":"A paradigm shift in the management of Cherubism? 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