{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T07:25:34Z","timestamp":1781249134255,"version":"3.54.1"},"reference-count":15,"publisher":"BMJ","issue":"12","funder":[{"DOI":"10.13039\/501100005809","name":"Hyderabad Eye Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2023,12,2]]},"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:p>A patient in his sixth decade presented to us with redness, pain and a deterioration of vision in his left eye. He had previously been diagnosed with lattice corneal dystrophy (LCD). He was diagnosed with microbial keratitis, and mixed infection was confirmed on culture (bacteria and fungus) with a protracted healing period before resolution of keratitis. He presented 2\u2009years later with similar issues in the same eye and was noted to have a second episode of microbial keratitis, with microsporidia spores noted on gram, potassium hydroxide and calcofluor white stains. He was diagnosed with microsporidial stromal keratitis and underwent therapeutic penetrating keratoplasty. Unfortunately, he suffered a recurrence of microsporidial keratitis following surgery with eventual transplant failure. Microsporidia as an infection in LCD has, to our knowledge, not been previously reported. We aim to discuss microsporidial infection and recurrent microbial keratitis in the setting of LCD.<\/jats:p>","DOI":"10.1136\/bcr-2023-255143","type":"journal-article","created":{"date-parts":[[2023,12,19]],"date-time":"2023-12-19T12:40:45Z","timestamp":1702989645000},"page":"e255143","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Microbial keratitis in lattice corneal dystrophy: microsporidia as a new cause"],"prefix":"10.1136","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8733-8853","authenticated-orcid":false,"given":"Anirban","family":"Dutta","sequence":"first","affiliation":[{"name":"Cornea & Anterior Segment Services, LV Prasad Eye Institute Bhubaneswar Campus, Bhubaneswar, Odisha, India"},{"name":"Cornea Services, Chirag Eye Care, Prayagraj, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sujata","family":"Das","sequence":"additional","affiliation":[{"name":"Cornea & Anterior Segment Services, LV Prasad Eye Institute Bhubaneswar Campus, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Smruti Rekha","family":"Priyadarshini","sequence":"additional","affiliation":[{"name":"Cornea & Anterior Segment Services, LV Prasad Eye Institute Bhubaneswar Campus, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dilip K","family":"Mishra","sequence":"additional","affiliation":[{"name":"Ophthalmic Pathology Laboratory, LV Prasad Eye Institute, Hyderabad, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2023,12,19]]},"reference":[{"key":"2025082800012292000_16.12.e255143.1","doi-asserted-by":"crossref","first-page":"e9","DOI":"10.1097\/ICO.0000000000000765","article-title":"Reply to letter to the editor: Ultrathin grafts for DSAEK with a single microkeratome pass","volume":"35","author":"Choulakian","year":"2016","journal-title":"Cornea"},{"key":"2025082800012292000_16.12.e255143.2","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0000000000000307"},{"key":"2025082800012292000_16.12.e255143.3","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.11-7771"},{"key":"2025082800012292000_16.12.e255143.4","doi-asserted-by":"crossref","first-page":"2313","DOI":"10.1177\/1120672120968724","article-title":"Contact lens induced bacterial keratitis in LCD II: management and multimodal imaging: a case report and review of literature","volume":"31","author":"Alafaleq","year":"2021","journal-title":"Eur J Ophthalmol"},{"key":"2025082800012292000_16.12.e255143.5","doi-asserted-by":"crossref","first-page":"162","DOI":"10.4103\/0301-4738.60097","article-title":"Fungal keratitis in lattice dystrophy","volume":"58","author":"Chatterjee","year":"2010","journal-title":"Indian J Ophthalmol"},{"key":"2025082800012292000_16.12.e255143.6","doi-asserted-by":"crossref","unstructured":"Garg P . 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