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Here, we describe a patient case with an atypical presentation of digital ischaemia and present a brief review on prior reports of digital ischaemia related to cancer.<\/jats:p>","DOI":"10.1136\/bcr-2023-255165","type":"journal-article","created":{"date-parts":[[2023,4,13]],"date-time":"2023-04-13T13:31:14Z","timestamp":1681392674000},"page":"e255165","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Examining the differential of digital ischaemia and review of paraneoplastic ischaemia"],"prefix":"10.1136","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9326-4635","authenticated-orcid":false,"given":"Lauran","family":"Zeineddine","sequence":"first","affiliation":[{"name":"Internal Medicine, University of Florida, Gainesville, Florida, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diana","family":"Gomez-Manjarres","sequence":"additional","affiliation":[{"name":"Pulmonary and Critical Care Medicine, University of Florida, Gainesville, Florida, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2023,4,13]]},"reference":[{"key":"2025082800293482000_16.4.e255165.1","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000000047","article-title":"Digital ischemia associated with cancer: results from a cohort study","volume":"93","author":"Le Besnerais","year":"2014","journal-title":"Medicine (Baltimore)"},{"key":"2025082800293482000_16.4.e255165.2","first-page":"391","article-title":"Pseudo-raynaud\u2019s: cryoglobulinemia secondary to occult neoplasm","volume":"95","author":"Domz","year":"1961","journal-title":"Calif Med"},{"key":"2025082800293482000_16.4.e255165.3","first-page":"1279","article-title":"Relationship between digital necrosis of the upper limbs and malignant conditions (author\u2019s transl)","volume":"7","author":"Vayssairat","year":"1978","journal-title":"Nouv Presse Med"},{"key":"2025082800293482000_16.4.e255165.4","first-page":"800","article-title":"Digital necrosis: a paraneoplastic syndrome","volume":"12","author":"Petri","year":"1985","journal-title":"J Rheumatol"},{"key":"2025082800293482000_16.4.e255165.5","first-page":"370","article-title":"Digital ischemia associated with lung cancer: a case report","volume":"57","author":"Wang","year":"1996","journal-title":"Zhonghua Yi Xue Za Zhi (Taipei)"},{"key":"2025082800293482000_16.4.e255165.6","unstructured":"Godeau P , Herreman G , Lanoe R , et al . 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