{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T08:25:42Z","timestamp":1790151942048,"version":"4.0.1"},"reference-count":22,"publisher":"BMJ","issue":"4","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2024,4,6]]},"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:p>Multiple evanescent white dot syndrome (MEWDS) is a rare inflammatory eye condition. We report an atypical case of MEWDS in a man in his 30s who presented with blurred vision (visual acuity 6\/9), floaters and photopsia in his left eye. Funduscopy examination showed mild peripheral nasal vascular sheathing with subtle grey-white dots highlighted on fundus autofluorescence. As far as the authors are aware, this is the first case presentation whereby areas affected by MEWDS started in the peripheral retina and migrated centrally. Fluorescein angiography showed hyperfluorescent areas in wreath-like patterns nasally. Optical coherence tomography showed disruption of the ellipsoid zone and hyperreflective projections into the outer nuclear layer. The size of the involved area increased over 3 weeks and subsequently resolved over 4 months. Simultaneously, the patient\u2019s symptoms also resolved, without treatment. This case highlights the importance of multimodal imaging, especially ultrawidefield imaging in diagnosing MEWDS.<\/jats:p>","DOI":"10.1136\/bcr-2023-255522","type":"journal-article","created":{"date-parts":[[2024,4,29]],"date-time":"2024-04-29T13:50:37Z","timestamp":1714398637000},"page":"e255522","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Atypical multiple evanescent white dot syndrome presenting with peripheral retinal lesions"],"prefix":"10.1136","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5758-7346","authenticated-orcid":false,"given":"Jae Yee","family":"Ku","sequence":"first","affiliation":[{"name":"Eye and Vision Science, University of Liverpool, Liverpool, UK"},{"name":"Ophthalmology, Royal Bolton Hospital NHS Foundation Trust, Bolton, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nyaish","family":"Mansoor","sequence":"additional","affiliation":[{"name":"Ophthalmology, Royal Bolton Hospital NHS Foundation Trust, Bolton, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdelsattar","family":"Farrag","sequence":"additional","affiliation":[{"name":"Ophthalmology, Royal Bolton Hospital NHS Foundation Trust, Bolton, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2024,4,29]]},"reference":[{"key":"2025082711044015000_17.4.e255522.1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1984.01040030527008"},{"key":"2025082711044015000_17.4.e255522.2","doi-asserted-by":"crossref","first-page":"426","DOI":"10.3109\/09273948.2011.624287","article-title":"White DOT syndromes: a 20-year study of incidence, clinical features, and outcomes","volume":"19","author":"Abu-Yaghi","year":"2011","journal-title":"Ocul Immunol Inflamm"},{"key":"2025082711044015000_17.4.e255522.3","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.ajo.2021.03.050","article-title":"Classification criteria for multiple evanescent white DOT syndrome","volume":"228","year":"2021","journal-title":"Am J Ophthalmol"},{"key":"2025082711044015000_17.4.e255522.4","doi-asserted-by":"crossref","unstructured":"Papasavvas I , Mantovani A , Tugal-Tutkun I , et al . Multiple evanescent white DOT syndrome (MEWDS): update on practical appraisal, diagnosis and Clinicopathology; a review and an alternative comprehensive perspective. 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Multiple evanescent white DOT syndrome. 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Multiple evanescent white DOT syndrome: bilateral disease may be silent and asymmetric. Am J Ophthalmol Case Rep 2021;21. doi:10.1016\/j.ajoc.2020.101004","DOI":"10.1016\/j.ajoc.2020.101004"},{"key":"2025082711044015000_17.4.e255522.20","doi-asserted-by":"crossref","unstructured":"Ng CC , Jumper JM , Cunningham ET . Multiple evanescent white DOT syndrome following influenza immunization - A Multimodal imaging study. 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