{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T23:36:18Z","timestamp":1793316978959,"version":"4.5.0"},"reference-count":19,"publisher":"BMJ","issue":"11","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2023,10,20]]},"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:p>A woman with severe type III osteogenesis imperfecta spontaneously conceived a monochorionic, diamniotic twin pregnancy. Due to the severity of her condition, her pregnancy required close follow-up involving a multidisciplinary team, including high-risk obstetricians, anaesthetists, pulmonologists and respiratory therapists. Eventually, the twins were delivered via caesarean section at 26 weeks\u2019 gestation.<\/jats:p>\n               <jats:p>We discuss the challenges and considerations in managing her high-risk pregnancy, highlighting the importance of multidisciplinary care in achieving a safe outcome for mother and babies.<\/jats:p>","DOI":"10.1136\/bcr-2023-255738","type":"journal-article","created":{"date-parts":[[2023,11,15]],"date-time":"2023-11-15T13:01:03Z","timestamp":1700053263000},"page":"e255738","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Monochorionic twin pregnancy in a patient with type III osteogenesis imperfecta: a multidisciplinary challenge"],"prefix":"10.1136","volume":"16","author":[{"given":"Kai Wei","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynaecology, KK Women's and Children's Hospital, Singapore"},{"name":"Department of Obstetrics and Gynaecology, Singapore General Hospital, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"May Un Sam","family":"Mok","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, Singapore General Hospital, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui Zhong","family":"Chai","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liying","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Singapore General Hospital, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2023,11,15]]},"reference":[{"key":"2025082723162589000_16.11.e255738.1","doi-asserted-by":"crossref","DOI":"10.3390\/medicina57050464","article-title":"Current overview of osteogenesis imperfecta","volume":"57","author":"Deguchi","year":"2021","journal-title":"Medicina (Kaunas)"},{"key":"2025082723162589000_16.11.e255738.2","unstructured":"Steiner RD , Basel D . Col1A1\/2 Osteogenesis Imperfecta. In: Adam MP , Everman DB , Mirzaa GM , et al , eds. GeneReviews(\u00ae). Seattle (WA): University of Washington, Seattle Copyright \u00a9 1993-2023, University of Washington, Seattle. GeneReviews is a registered trademark of the University of Washington, Seattle. All rights reserved, 1993."},{"key":"2025082723162589000_16.11.e255738.3","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1097\/00000539-200205000-00049","article-title":"Pregnancy complicated by severe osteogenesis imperfecta: a report of two cases","volume":"94","author":"Vogel","year":"2002","journal-title":"Anesth Analg"},{"key":"2025082723162589000_16.11.e255738.4","doi-asserted-by":"crossref","first-page":"1676","DOI":"10.1080\/07853890.2021.1980819","article-title":"Pathophysiology of respiratory failure in patients with osteogenesis imperfecta: a systematic review","volume":"53","author":"Storoni","year":"2021","journal-title":"Ann Med"},{"key":"2025082723162589000_16.11.e255738.5","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1111\/cge.13440","article-title":"A multicenter study to evaluate pulmonary function in osteogenesis imperfecta","volume":"94","author":"Tam","year":"2018","journal-title":"Clin Genet"},{"key":"2025082723162589000_16.11.e255738.6","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.ijoa.2014.07.006","article-title":"Osteogenesis imperfecta: cesarean deliveries in identical twins","volume":"24","author":"Dinges","year":"2015","journal-title":"Int J Obstet Anesth"},{"key":"2025082723162589000_16.11.e255738.7","doi-asserted-by":"crossref","first-page":"1252","DOI":"10.1002\/ccr3.1549","article-title":"Pregnancies complicated by maternal osteogenesis Imperfecta type III: a case report and review of literature","volume":"6","author":"Kawakita","year":"2018","journal-title":"Clin Case Rep"},{"key":"2025082723162589000_16.11.e255738.8","doi-asserted-by":"crossref","first-page":"100362","DOI":"10.1016\/j.ajogmf.2021.100362","article-title":"Pregnancy in women with osteogenesis imperfecta: pregnancy characteristics, maternal, and neonatal outcomes","volume":"3","author":"Rao","year":"2021","journal-title":"Am J Obstet Gynecol MFM"},{"key":"2025082723162589000_16.11.e255738.9","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1038\/jp.2016.111","article-title":"Pregnancy outcomes in women with osteogenesis imperfecta: a retrospective cohort study","volume":"36","author":"Ruiter-Ligeti","year":"2016","journal-title":"J Perinatol"},{"key":"2025082723162589000_16.11.e255738.10","doi-asserted-by":"crossref","first-page":"2358","DOI":"10.3109\/14767058.2015.1085965","article-title":"Pregnancy outcomes in women with osteogenesis imperfecta","volume":"29","author":"Yimgang","year":"2016","journal-title":"J Matern Fetal Neonatal Med"},{"key":"2025082723162589000_16.11.e255738.11","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1038\/gim.2015.131","article-title":"Cesarean delivery is not associated with decreased at-birth fracture rates in osteogenesis imperfecta","volume":"18","author":"Bellur","year":"2016","journal-title":"Genet Med"},{"key":"2025082723162589000_16.11.e255738.12","doi-asserted-by":"crossref","DOI":"10.1080\/01443610220130689","article-title":"Management of pregnancy complicated by maternal osteogenesis imperfecta. Report of a case with uterine rupture","volume":"22","author":"Krishnamoorthy","year":"2002","journal-title":"J Obstet Gynaecol"},{"key":"2025082723162589000_16.11.e255738.13","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1111\/j.1365-2044.1996.tb12619.x","article-title":"Osteogenesis Imperfecta and malignant hyperthermia","volume":"51","author":"Porsborg","year":"1996","journal-title":"Anaesthesia"},{"key":"2025082723162589000_16.11.e255738.14","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1111\/bjh.16097","article-title":"Bleeding and bruising in osteogenesis imperfecta: International society on thrombosis and haemostasis bleeding assessment tool and haemostasis laboratory assessment in 22 individuals","volume":"187","author":"Gooijer","year":"2019","journal-title":"Br J Haematol"},{"key":"2025082723162589000_16.11.e255738.15","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1097\/00000542-200210000-00039","article-title":"Osteogenesis Imperfecta, perioperative bleeding, and desmopressin","volume":"97","author":"Keegan","year":"2002","journal-title":"Anesthesiology"},{"key":"2025082723162589000_16.11.e255738.16","unstructured":"Royal College of Obstetricians and Gynaecologists . Reducing the risk of venous thromboembolism during pregnancy and the puerperium; 2015."},{"key":"2025082723162589000_16.11.e255738.17","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1055\/s-0030-1248137","article-title":"Injectable contraception","volume":"28","author":"Roy","year":"2010","journal-title":"Semin Reprod Med"},{"key":"2025082723162589000_16.11.e255738.18","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2020.00603","article-title":"Hormonal contraception and bone health in adolescents","volume":"11","author":"Bachrach","year":"2020","journal-title":"Front Endocrinol (Lausanne)"},{"key":"2025082723162589000_16.11.e255738.19","doi-asserted-by":"crossref","DOI":"10.1186\/s12978-020-01054-y","article-title":"A systematic review on clinical effectiveness, side-effect profile and meta-analysis on continuation rate of Etonogestrel contraceptive implant","volume":"18","author":"Moray","year":"2021","journal-title":"Reprod Health"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2023-255738","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T06:16:37Z","timestamp":1756361797000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2023-255738"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11]]},"references-count":19,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2023,11,15]]},"published-print":{"date-parts":[[2023,11]]}},"alternative-id":["10.1136\/bcr-2023-255738"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2023-255738","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,11]]}}}