{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T18:10:01Z","timestamp":1756318201475,"version":"3.44.0"},"reference-count":15,"publisher":"BMJ","issue":"8","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2023,8,8]]},"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:p>A man in his 50s presented to plastic surgery again with a lesion on his left upper arm. He had previously been treated for a malignant melanoma (MM) on his right arm over 5\u2009years earlier. Sentinel lymph node biopsy (SLNB) had been negative, and he had completed the recommended 5\u2009years follow-up period. Imaging was suspicious for an intramuscular soft tissue malignancy within the triceps muscle. After discussion with the regional sarcoma service, a core biopsy was performed. Histopathology suggested a diagnosis of metastatic MM, which was confirmed after surgical excision. This case highlights a rare example of an isolated muscular metastasis of MM, which presented at a distant site, over 5\u2009years from the original treatment. This case highlights the unpredictable nature of MM, reminding clinicians of the need for a low threshold for investigation of soft tissue masses in patients with a history of cutaneous malignancy.<\/jats:p>","DOI":"10.1136\/bcr-2023-255819","type":"journal-article","created":{"date-parts":[[2023,8,28]],"date-time":"2023-08-28T00:40:54Z","timestamp":1693183254000},"page":"e255819","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Atypical late presentation of muscular metastasis of melanoma in the contralateral limb"],"prefix":"10.1136","volume":"16","author":[{"given":"Ankita","family":"Mondal","sequence":"first","affiliation":[{"name":"Department of Plastic Surgery, Ninewells Hospital and Medical School, Dundee, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lewis","family":"Dingle","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Ninewells Hospital and Medical School, Dundee, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew","family":"Hough","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Ninewells Hospital and Medical School, Dundee, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2023,8,27]]},"reference":[{"key":"2025082710555170000_16.8.e255819.1","unstructured":"Cancer Research UK . Melanoma skin cancer statistics. 2022. Available: https:\/\/www.cancerresearchuk.org\/health-professional\/cancer-statistics\/statistics-by-cancer-type\/melanoma-skin-cancer#heading-Zero"},{"key":"2025082710555170000_16.8.e255819.2","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2016.304"},{"key":"2025082710555170000_16.8.e255819.3","unstructured":"National Institute for Health and Care Excellence (NICE) . Melanoma: assessment and management (NG14) [NICE]. 2015. Available: nice.org.uk"},{"key":"2025082710555170000_16.8.e255819.4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra2034861"},{"key":"2025082710555170000_16.8.e255819.5","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.1007\/s11912-022-01289-x","article-title":"Surgical management of melanoma: advances and updates","volume":"24","author":"Santamaria-Barria","year":"2022","journal-title":"Curr Oncol Rep"},{"key":"2025082710555170000_16.8.e255819.6","doi-asserted-by":"publisher","DOI":"10.1080\/14737140.2018.1489246"},{"key":"2025082710555170000_16.8.e255819.7","first-page":"289","article-title":"Evaluating soft-tissue lumps and bumps","volume":"114","author":"Church","year":"2017","journal-title":"Mo Med"},{"key":"2025082710555170000_16.8.e255819.8","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/1470-7330-14-21","article-title":"Muscle metastases: comparison of features in different primary tumours","volume":"14","author":"Surov","year":"2014","journal-title":"Cancer Imaging"},{"key":"2025082710555170000_16.8.e255819.9","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/S0001-7310(07)70128-X","article-title":"Longitudinal study of different metastatic patterns in the progression of cutaneous melanoma","volume":"98","author":"Tejera-Vaquerizo","year":"2007","journal-title":"Actas Dermosifiliogr"},{"key":"2025082710555170000_16.8.e255819.10","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2002.04867.x"},{"key":"2025082710555170000_16.8.e255819.11","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2004.12.001"},{"key":"2025082710555170000_16.8.e255819.12","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1097\/CMR.0000000000000466","article-title":"Skeletal muscle and solitary bone metastases from malignant melanoma: multimodality imaging and oncological outcome","volume":"28","author":"G\u00f3mez-Le\u00f3n","year":"2018","journal-title":"Melanoma Res"},{"key":"2025082710555170000_16.8.e255819.13","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1097\/00003086-199810000-00029","article-title":"Metastatic carcinoma to skeletal muscle. A report of 15 patients","volume":"1998","author":"Herring","year":"1998","journal-title":"Clin Orthop Relat Res"},{"key":"2025082710555170000_16.8.e255819.14","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1002\/jso.24743","article-title":"Predictors of false negative sentinel lymph node biopsy in trunk and extremity melanoma","volume":"116","author":"Sinnamon","year":"2017","journal-title":"J Surg Oncol"},{"key":"2025082710555170000_16.8.e255819.15","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/j.soc.2014.12.012","article-title":"Long-term follow-up for melanoma patients: is there any evidence of a benefit","volume":"24","author":"Rueth","year":"2015","journal-title":"Surg Oncol Clin N Am"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2023-255819","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T17:55:58Z","timestamp":1756317358000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2023-255819"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8]]},"references-count":15,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2023,8,27]]},"published-print":{"date-parts":[[2023,8]]}},"alternative-id":["10.1136\/bcr-2023-255819"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2023-255819","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2023,8]]}}}