{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T02:45:58Z","timestamp":1776739558760,"version":"3.51.2"},"reference-count":9,"publisher":"BMJ","issue":"11","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2023,10,7]]},"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:p>Protein C deficiency is a rare blood disorder that increases the risk of thromboembolism, resulting in deep vein thrombosis, pulmonary embolisms and strokes. Segmental testicular infarction is also a rare condition with unclear aetiology. This case presents a man in his 50s with protein C deficiency who developed a segmental testicular infarction. The patient was managed conservatively, without surgical intervention. He was monitored with serial ultrasound, which demonstrated progression from normal testis to segmental infarction and eventually resolution. The case highlights that protein C deficiency can cause testicular infarction, and a multidisciplinary approach can help avoid unnecessary surgery with excellent outcomes. Segmental infarction should be considered in patients with pre-existing thrombophilias after excluding malignancy and infection. Conservative management with repeat ultrasonography and follow-up can be appropriate in such cases.<\/jats:p>","DOI":"10.1136\/bcr-2023-255915","type":"journal-article","created":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T13:09:47Z","timestamp":1698844187000},"page":"e255915","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Segmental testicular infarction secondary to protein C deficiency"],"prefix":"10.1136","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0398-1265","authenticated-orcid":false,"given":"Damien","family":"Gibson","sequence":"first","affiliation":[{"name":"Medicine, University of New South Wales, Sydney, New South Wales, Australia"},{"name":"Urology, Saint George Hospital, Kogarah, New South Wales, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenjie","family":"Zhong","sequence":"additional","affiliation":[{"name":"Urology, Saint George Hospital, Kogarah, New South Wales, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohit","family":"Bajaj","sequence":"additional","affiliation":[{"name":"Urology, Saint George Hospital, Kogarah, New South Wales, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anu","family":"Ranasinghe","sequence":"additional","affiliation":[{"name":"Urology, Saint George Hospital, Kogarah, New South Wales, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2023,11,1]]},"reference":[{"key":"2025082622394385000_16.11.e255915.1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2516.2008.01838.x"},{"key":"2025082622394385000_16.11.e255915.2","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-007-0674-2"},{"key":"2025082622394385000_16.11.e255915.3","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)67838-X"},{"key":"2025082622394385000_16.11.e255915.4","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.afju.2017.09.006","article-title":"Bilateral spontaneous thrombosis of the pampiniform plexus; a rare etiology of acute scrotal pain: a case report and review of literature","volume":"24","author":"Kamel","year":"2018","journal-title":"Afr J Urol"},{"key":"2025082622394385000_16.11.e255915.5","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1007\/s10140-011-0999-7","article-title":"Segmental testicular infarction: report of seven new cases and literature review","volume":"19","author":"Saxon","year":"2012","journal-title":"Emerg Radiol"},{"key":"2025082622394385000_16.11.e255915.6","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.2214\/ajr.184.5.01841587","article-title":"Radiologic findings of segmental testicular infarction","volume":"184","author":"Fern\u00e1ndez-P\u00e9rez","year":"2005","journal-title":"AJR Am J Roentgenol"},{"key":"2025082622394385000_16.11.e255915.7","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000070822.60491.d4"},{"key":"2025082622394385000_16.11.e255915.8","article-title":"Segmental testicular infarction: a case report of a rare condition","volume":"43","author":"Saidani","year":"2022","journal-title":"Urol Case Rep"},{"key":"2025082622394385000_16.11.e255915.9","article-title":"Segmental testicular infarction: a case report","volume":"14","author":"Almalki","year":"2022","journal-title":"Cureus"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2023-255915","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T05:39:49Z","timestamp":1756273189000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2023-255915"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11]]},"references-count":9,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2023,11,1]]},"published-print":{"date-parts":[[2023,11]]}},"alternative-id":["10.1136\/bcr-2023-255915"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2023-255915","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,11]]}}}