{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T19:40:03Z","timestamp":1756323603061,"version":"3.44.0"},"reference-count":10,"publisher":"BMJ","issue":"1","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2023,12,20]]},"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:p>Group III pulmonary hypertension (PH) is common in patients with hypersensitivity pneumonitis (HSP). Group I PH and vasoreactivity in HSP have not been reported. We describe a case of an elderly veterinarian woman who presented with progressive shortness of breath and desaturation on exertion. The patient was diagnosed with non-fibrotic HSP after consistent findings on chest CT, transbronchial biopsy and a positive HSP serological panel. The patient relocated her birds, and prednisone was started. Due to persistent symptoms, she underwent a right heart catheterisation, which showed PH with vasoreactivity; subsequently, nifedipine was started. Over a 9-month follow-up, there was an improvement in symptoms and a complete resolution of PH and CT scan changes. Our case highlights the rare possibility of group I PH in HSP. It illustrates the importance of confirming the aetiology of PH and initiating treatment early to resolve symptoms.<\/jats:p>","DOI":"10.1136\/bcr-2023-255921","type":"journal-article","created":{"date-parts":[[2024,1,10]],"date-time":"2024-01-10T00:42:37Z","timestamp":1704847357000},"page":"e255921","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Vasoreactive pulmonary artery hypertension in non-fibrotic hypersensitive pneumonitis"],"prefix":"10.1136","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8544-3980","authenticated-orcid":false,"given":"Sushan","family":"Gupta","sequence":"first","affiliation":[{"name":"Carle Foundation Hospital, Urbana, Illinois, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Avani","family":"Mohta","sequence":"additional","affiliation":[{"name":"Carle Foundation Hospital, Urbana, Illinois, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danish","family":"Thameem","sequence":"additional","affiliation":[{"name":"Pulmonary and Critical Care Medicine, Carle Foundation Hospital, Urbana, Illinois, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2024,1,5]]},"reference":[{"key":"2025082712083126000_17.1.e255921.1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00010414"},{"key":"2025082712083126000_17.1.e255921.2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra2000348"},{"key":"2025082712083126000_17.1.e255921.3","doi-asserted-by":"crossref","DOI":"10.1183\/13993003.00879-2022","article-title":"ESC\/ERS guidelines for the diagnosis and treatment of pulmonary hypertension","volume":"61","author":"Humbert","year":"2023","journal-title":"Eur Respir J"},{"key":"2025082712083126000_17.1.e255921.4","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(91)90556-O"},{"key":"2025082712083126000_17.1.e255921.5","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.104.488486"},{"key":"2025082712083126000_17.1.e255921.6","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.rmed.2019.03.004","article-title":"Outcomes of lung disease-associated pulmonary hypertension and impact of elevated pulmonary vascular resistance","volume":"150","author":"Awerbach","year":"2019","journal-title":"Respir Med"},{"key":"2025082712083126000_17.1.e255921.7","doi-asserted-by":"crossref","first-page":"1651","DOI":"10.1016\/j.chest.2020.04.046","article-title":"The trouble with group 3 pulmonary hypertension in interstitial lung disease: dilemmas in diagnosis and the conundrum of treatment","volume":"158","author":"King","year":"2020","journal-title":"Chest"},{"key":"2025082712083126000_17.1.e255921.8","doi-asserted-by":"crossref","DOI":"10.1186\/s12890-023-02347-1","article-title":"Predictors of pulmonary hypertension in patients with hypersensitivity pneumonitis","volume":"23","author":"Elnady","year":"2023","journal-title":"BMC Pulm Med"},{"key":"2025082712083126000_17.1.e255921.9","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1007\/s00408-016-9905-0","article-title":"Pulmonary vascular capacitance is associated with vasoreactivity and long-term response to calcium channel blockers in idiopathic pulmonary arterial hypertension","volume":"194","author":"Cheng","year":"2016","journal-title":"Lung"},{"key":"2025082712083126000_17.1.e255921.10","doi-asserted-by":"crossref","DOI":"10.1183\/16000617.0167-2019","article-title":"Prognostic factors in chronic hypersensitivity pneumonitis","volume":"29","author":"Creamer","year":"2020","journal-title":"Eur Respir Rev"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2023-255921","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T19:08:39Z","timestamp":1756321719000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2023-255921"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":10,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,1,5]]},"published-print":{"date-parts":[[2024,1]]}},"alternative-id":["10.1136\/bcr-2023-255921"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2023-255921","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2024,1]]}}}