{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:30:33Z","timestamp":1787837433264,"version":"build-2784847793"},"reference-count":22,"publisher":"BMJ","issue":"10","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2023,9,15]]},"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:p>A primiparous woman in her mid-30s presented at 31 weeks of gestation with a large vaginal mass obstructing the cervix, initially concerning for malignancy. Pelvic MRI confirmed a vaginal lesion located on the lateral wall, and histopathology diagnosed a giant condyloma acuminatum. The vaginal lesion was surgically resected at 34 weeks of gestation, and the patient proceeded to have a successful vaginal birth. Our case report demonstrates an unusual presentation of a rare anogenital disease and highlights a differential diagnosis for cervical and vaginal lesions.<\/jats:p>","DOI":"10.1136\/bcr-2023-255996","type":"journal-article","created":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T13:45:31Z","timestamp":1696340731000},"page":"e255996","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Giant condyloma acuminatum (Buschke-Lowenstein tumour) of the vagina during pregnancy"],"prefix":"10.1136","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1803-1254","authenticated-orcid":false,"given":"Stella Rose","family":"Harris","sequence":"first","affiliation":[{"name":"Department of Gynaecological Oncology, The Royal Hospital for Women, Randwick, New South Wales, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"King Man","family":"Wan","sequence":"additional","affiliation":[{"name":"Department of Gynaecological Oncology, The Royal Hospital for Women, Randwick, New South Wales, Australia"},{"name":"Faculty of Medicine, University of New South Wales, Sydney, New South Wales, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2023,10,3]]},"reference":[{"key":"2025082700053164000_16.10.e255996.1","doi-asserted-by":"crossref","first-page":"e263","DOI":"10.1097\/OLQ.0000000000001437","article-title":"Buschke-Lowenstein tumors: a review and proposed classification system","volume":"48","author":"Davis","year":"2021","journal-title":"Sex Transm Dis"},{"key":"2025082700053164000_16.10.e255996.2","doi-asserted-by":"crossref","first-page":"4547","DOI":"10.3390\/ijms23094547","article-title":"The pathogenesis of giant condyloma acuminatum (Buschke-Lowenstein tumor): an overview","volume":"23","author":"Purzycka-Bohdan","year":"2022","journal-title":"IJMS"},{"key":"2025082700053164000_16.10.e255996.3","doi-asserted-by":"publisher","DOI":"10.1007\/BF01728480"},{"key":"2025082700053164000_16.10.e255996.4","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/9919446","article-title":"Giant condyloma acuminata (Buschke-Lowenstein tumor): review of an unusual disease and difficult to manage","volume":"2021","author":"Nieves-Condoy","year":"2021","journal-title":"Infect Dis Obstet Gynecol"},{"key":"2025082700053164000_16.10.e255996.5","doi-asserted-by":"publisher","DOI":"10.1007\/BF02234473"},{"key":"2025082700053164000_16.10.e255996.6","doi-asserted-by":"publisher","DOI":"10.1007\/BF02052606"},{"key":"2025082700053164000_16.10.e255996.7","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/0090-8258(86)90032-6","article-title":"Condylomas of the uterine cervix initially interpreted as squamous carcinoma: a report of four cases including a lesion resembling the Buschke-Loewenstein giant condyloma","volume":"24","author":"Miles","year":"1986","journal-title":"Gynecol Oncol"},{"key":"2025082700053164000_16.10.e255996.8","first-page":"46","article-title":"Giant condyloma acuminatum of the endocervix and lower uterine segment","volume":"23","author":"Anderson","year":"1979","journal-title":"J Reprod Med"},{"key":"2025082700053164000_16.10.e255996.9","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/j.jogc.2021.10.011","article-title":"Clinical conundrum: a case of cervical giant condyloma acuminatum","volume":"44","author":"Arwini","year":"2022","journal-title":"J Obstet Gynaecol Can"},{"key":"2025082700053164000_16.10.e255996.10","first-page":"108","article-title":"Giant condylomas acuminata of the uterine Cervix in a pregnant woman","volume":"56","author":"Bogdanowicz","year":"1999","journal-title":"Przegl Lek"},{"key":"2025082700053164000_16.10.e255996.11","first-page":"328","article-title":"Buschke-Lowenstein tumor and pregnancy: a case report","volume":"28","author":"Crespo","year":"2007","journal-title":"Eur J Gynaecol Oncol"},{"key":"2025082700053164000_16.10.e255996.12","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1080\/00016340600617999","article-title":"The rapid development of a giant condyloma acuminatum (Buschke-Lowenstein tumor) during pregnancy","volume":"86","author":"Michiels","year":"2007","journal-title":"Acta Obstet Gynecol Scand"},{"key":"2025082700053164000_16.10.e255996.13","doi-asserted-by":"crossref","DOI":"10.1111\/dth.12972","article-title":"Giant condyloma acuminatum in pregnancy: a case report","volume":"32","author":"Cui","year":"2019","journal-title":"Dermatol Ther"},{"key":"2025082700053164000_16.10.e255996.14","first-page":"375","article-title":"Buschke-Loewenstein tumor during pregnancy. Apropos of 2 cases","volume":"85","author":"Picaud","year":"1990","journal-title":"Rev Fr Gynecol Obstet"},{"key":"2025082700053164000_16.10.e255996.15","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.gofs.2021.08.001","article-title":"La Tumeur de Buschke Lowenstein Chez La femme Enceinte","volume":"50","author":"Riethmuller","year":"2022","journal-title":"Gyn\u00e9cologie Obst\u00e9trique Fertilit\u00e9 & S\u00e9nologie"},{"key":"2025082700053164000_16.10.e255996.16","doi-asserted-by":"crossref","DOI":"10.3390\/microorganisms10101932","article-title":"Human papillomavirus infection during pregnancy and childhood: a comprehensive review","volume":"10","author":"Ardekani","year":"2022","journal-title":"Microorganisms"},{"key":"2025082700053164000_16.10.e255996.17","doi-asserted-by":"publisher","DOI":"10.1016\/0165-5876(95)01279-6"},{"key":"2025082700053164000_16.10.e255996.18","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.ijporl.2013.11.036","article-title":"Risk factors for the development and severity of juvenile-onset recurrent respiratory papillomatosis: a systematic review","volume":"78","author":"Niyibizi","year":"2014","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"2025082700053164000_16.10.e255996.19","doi-asserted-by":"crossref","DOI":"10.3390\/v12101119","article-title":"Detection of human papillomaviruses in the nasopharynx of breastfed infants: new findings and meta-analysis","volume":"12","author":"Dassi","year":"2020","journal-title":"Viruses"},{"key":"2025082700053164000_16.10.e255996.20","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0897.2010.00836.x"},{"key":"2025082700053164000_16.10.e255996.21","doi-asserted-by":"publisher","DOI":"10.1097\/00003081-198903000-00023"},{"key":"2025082700053164000_16.10.e255996.22","doi-asserted-by":"crossref","DOI":"10.1002\/rmv.2374","article-title":"Worldwide prevalence of human papillomavirus among pregnant women: a systematic review and meta-analysis","volume":"33","author":"Ardekani","year":"2023","journal-title":"Rev Med Virol"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2023-255996","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T07:05:39Z","timestamp":1756278339000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2023-255996"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10]]},"references-count":22,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2023,10,3]]},"published-print":{"date-parts":[[2023,10]]}},"alternative-id":["10.1136\/bcr-2023-255996"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2023-255996","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10]]}}}