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In view of neurological deterioration, he required urgent spinal decompression to preserve neurological function and prevent permanent paraplegia. Despite inadequate alpha-blockade, surgery was successful, and the perioperative course was uneventful. Alpha-blockade was subsequently optimised. Treatment with cyclophosphamide, vincristine and dacarbazine was started but, in view of disease progression, treatment was subsequently changed to sunitinib.<\/jats:p>","DOI":"10.1136\/bcr-2023-256052","type":"journal-article","created":{"date-parts":[[2023,9,12]],"date-time":"2023-09-12T20:36:40Z","timestamp":1694551000000},"page":"e256052","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Metastatic paraganglioma presenting with spinal cord compression requiring urgent surgery"],"prefix":"10.1136","volume":"16","author":[{"given":"Zachary","family":"Gauci","sequence":"first","affiliation":[{"name":"Department of Endocrinology and General Medicine, Mater Dei Hospital, Msida, Malta"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miriam","family":"Giordano Imbroll","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and General Medicine, Mater Dei Hospital, Msida, 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