{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T00:03:12Z","timestamp":1756425792689,"version":"3.44.0"},"reference-count":10,"publisher":"BMJ","issue":"8","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2023,8,14]]},"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:p>Verrucous carcinoma, a low-grade variant of squamous cell carcinoma, defined as a diagnostically squamous cell neoplasia involving lip, oropharyngeal, and laryngeal mucosa and named as \u2018Ackerman\u2019s tumour\u2019 by Ackerman in 1948. It usually occurs in the lower lip region and this is one such case in which a painful proliferative growth was evident over the right alveolar region for the period of 8 months. Radiological investigations, biopsies were performed followed by surgical excision of the lesion.<\/jats:p>","DOI":"10.1136\/bcr-2023-256239","type":"journal-article","created":{"date-parts":[[2023,8,30]],"date-time":"2023-08-30T12:10:51Z","timestamp":1693397451000},"page":"e256239","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Oral verrucous Carcinoma on mandibular right alveolar region"],"prefix":"10.1136","volume":"16","author":[{"given":"Ranjjith","family":"Ravichandar","sequence":"first","affiliation":[{"name":"Department of Oral Medicine and Radiology, Sri Balaji Vidyaapeeth (Deemed to be University), Indira Gandhi Institute of Dental Sciences, Pondicherry, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sivasankari","family":"Thirunavukarasu","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Radiology, Sri Balaji Vidyaapeeth (Deemed to be University), Indira Gandhi Institute of Dental Sciences, Pondicherry, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jagat","family":"Reddy","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Radiology, Sri Balaji Vidyaapeeth (Deemed to be University), Indira Gandhi Institute of Dental Sciences, Pondicherry, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sathyanarayanan","family":"Ramanujam","sequence":"additional","affiliation":[{"name":"Oral and Maxillofacial Surgery, Indira Gandhi Institute of Dental Sciences, Pondicherry, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2023,8,30]]},"reference":[{"key":"2025082801025349000_16.8.e256239.1","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1111\/jop.12422","article-title":"The AKT\/mTOR pathway is activated in Verrucous carcinoma of the oral cavity","volume":"45","author":"Chaisuparat","year":"2016","journal-title":"J Oral Pathol Med"},{"key":"2025082801025349000_16.8.e256239.2","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1016\/j.ijom.2010.03.014","article-title":"Relevance of human papilloma virus (HPV) infection to carcinogenesis of oral tongue cancer","volume":"39","author":"Lee","year":"2010","journal-title":"Int J Oral Maxillofac Surg"},{"doi-asserted-by":"publisher","key":"2025082801025349000_16.8.e256239.3","DOI":"10.1186\/1758-3284-1-8"},{"key":"2025082801025349000_16.8.e256239.4","first-page":"1772","article-title":"Human Papillomavirus and oral cancer: the International agency for research on cancer multicenter study","volume":"95","author":"Herrero","year":"2003","journal-title":"CancerSpectrum Knowledge Environment"},{"key":"2025082801025349000_16.8.e256239.5","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1055\/s-0039-1697831","article-title":"Oral Verrucous carcinoma: a study of 12 cases","volume":"4","author":"Alkan","year":"2010","journal-title":"Eur J Dent"},{"key":"2025082801025349000_16.8.e256239.6","first-page":"57","article-title":"A clinic study on oral Verrucous carcinoma phenotypes","volume":"8","author":"Tang","year":"2005","journal-title":"Chin J Dent Res"},{"key":"2025082801025349000_16.8.e256239.7","doi-asserted-by":"crossref","first-page":"59","DOI":"10.3892\/ijo.2016.3501","article-title":"Oral Verrucous carcinoma: from Multifactorial etiology to diverse treatment regimens (review)","volume":"49","author":"Peng","year":"2016","journal-title":"Int J Oncol"},{"key":"2025082801025349000_16.8.e256239.8","doi-asserted-by":"crossref","first-page":"e30","DOI":"10.1016\/j.tripleo.2006.09.011","article-title":"Cyclin D1 expression in oral squamous cell carcinoma and Verrucous carcinoma: correlation with histological differentiation","volume":"103","author":"Angadi","year":"2007","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"doi-asserted-by":"publisher","key":"2025082801025349000_16.8.e256239.9","DOI":"10.1002\/1097-0142(20001215)89:12<2597::AID-CNCR12>3.0.CO;2-N"},{"doi-asserted-by":"publisher","key":"2025082801025349000_16.8.e256239.10","DOI":"10.1002\/1097-0142(19801015)46:8<1855::AID-CNCR2820460825>3.0.CO;2-#"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2023-256239","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T08:02:58Z","timestamp":1756368178000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2023-256239"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8]]},"references-count":10,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2023,8,30]]},"published-print":{"date-parts":[[2023,8]]}},"alternative-id":["10.1136\/bcr-2023-256239"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2023-256239","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2023,8]]}}}